Results 71 to 80 of about 17,151,919 (277)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Fitting of parameters for a temperature control model by means of continuous derivative-free optimization: a case study in a broiler house

open access: yesBulletin of Computational Applied Mathematics, 2017
Intensive broiler production requires of accurate control systems aimed to maintain ideal conditions inside the facilities. The achievement of an appropriate environment guarantees good performance and sustainability of the production.
Bruno H. Cervelin   +4 more
doaj  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Novel Techniques with Memory Extension of Three-Step Derivative-Free Iterative Scheme for Nonlinear Systems

open access: yesComputation
This article presents the development of three-step derivative-free techniques with memory, which achieve higher convergence orders for solving systems of nonlinear equations.
Nishant Kumar   +2 more
doaj   +1 more source

A Family of Derivative-Free Methods with High Order of Convergence and Its Application to Nonsmooth Equations

open access: yesAbstract and Applied Analysis, 2012
A family of derivative-free methods of seventh-order convergence for solving nonlinear equations is suggested. In the proposed methods, several linear combinations of divided differences are used in order to get a good estimation of the derivative of the
Alicia Cordero   +3 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Derivative free multilevel optimization methods

open access: yes, 2009
Derivative free optimization algorithms are implementations of trust region based derivative-free methods using multivariate polynomial interpolation.
BENGİSEN PEKMEN
core  

Derivative-Free Iterative Methods for Solving Nonlinear Equations [PDF]

open access: yes, 2014
: In this paper, we suggest and analyze some new derivative free iterative methods for solving nonlinear equation f(x)=0 using a suitable transformation. We also give several examples to illustrate the efficiency of these methods.
Aslam Noor, Muhammad   +5 more
core   +1 more source

Avoiding Geometry Improvement in Derivative-Free Model-Based Methods via Randomization [PDF]

open access: yes, 2023
We present a technique for model-based derivative-free optimization called \emph{basis sketching}. Basis sketching consists of taking random sketches of the Vandermonde matrix employed in constructing an interpolation model.
Menickelly, Matt
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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