Results 81 to 90 of about 1,072,002 (279)
A General Class of Derivative Free Optimal Root Finding Methods Based on Rational Interpolation
We construct a new general class of derivative free n-point iterative methods of optimal order of convergence 2n-1 using rational interpolant. The special cases of this class are obtained.
Fiza Zafar +3 more
doaj +1 more source
Challenges with bearings only tracking for missile guidance systems and how to cope with them. [PDF]
This paper addresses the problem of closed loop missile guidance using bearings and target angular extent information. Comparison is performed between particle filtering methods and derivative free methods.
Mihaylova, Lyudmila +2 more
core
On Derivative-Free Optimisation Methods
As part of the field of mathematical optimisation, derivative-free optimisation is the study of optimisation methods that are not granted full access to the derivative of the objective function. In this master's thesis, three derivative-free optimisation methods known from the literature that do not use the derivatives have been studied, namely the ...
openaire +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Systems and Methods for Derivative-Free Adaptive Control [PDF]
An adaptive control system is disclosed. The control system can control uncertain dynamic systems. The control system can employ one or more derivative-free adaptive control architectures. The control system can further employ one or more derivative-free
Calise, Anthony J. +2 more
core +1 more source
Metric-Free Natural Gradient for Joint-Training of Boltzmann Machines [PDF]
This paper introduces the Metric-Free Natural Gradient (MFNG) algorithm for training Boltzmann Machines. Similar in spirit to the Hessian-Free method of Martens [8], our algorithm belongs to the family of truncated Newton methods and exploits an ...
Bengio, Yoshua +3 more
core
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
In this paper, a derivative-free conjugate gradient method for solving nonlinear equations with convex constraints is proposed. The proposed method can be viewed as an extension of the three-term modified Polak-Ribiére-Polyak method (TTPRP) and ...
Abdulkarim Hassan Ibrahim +2 more
doaj +1 more source
Optimizing Photonic Nanostructures via Multi-fidelity Gaussian Processes [PDF]
We apply numerical methods in combination with finite-difference-time-domain (FDTD) simulations to optimize transmission properties of plasmonic mirror color filters using a multi-objective figure of merit over a five-dimensional parameter space by ...
Atwater, Harry A. +6 more
core +1 more source

