Results 31 to 40 of about 66,605 (263)

Calibrating the GAMIL3-1° climate model using a derivative-free optimization method [PDF]

Geoscientific Model Development
Parameterization in climate models often involves parameters that are poorly constrained by observations or theoretical understanding alone. Manual tuning by experts can be time-consuming, subjective, and prone to underestimating uncertainties. Automated
W. Liang, W. Liang, W. Liang, S. F. B. Tett, L. Li, C. Cartis, D. Xu, W. Dong, W. Dong, J. Huang, J. Huang   +10 more
doaj   +1 more source

RF cavity design exploiting a new derivative-free trust region optimization approach

Journal of Advanced Research, 2015
In this article, a novel derivative-free (DF) surrogate-based trust region optimization approach is proposed. In the proposed approach, quadratic surrogate models are constructed and successively updated.
Abdel-Karim S.O. Hassan, Hany L. Abdel-Malek, Ahmed S.A. Mohamed, Tamer M. Abuelfadl, Ahmed E. Elqenawy   +4 more
doaj   +1 more source

Derivative-free nonlinear optimization filter simplex [PDF]

International Journal of Applied Mathematics and Computer Science, 2010
Derivative-free nonlinear optimization filter simplexThe filter method is a technique for solving nonlinear programming problems. The filter algorithm has two phases in each iteration. The first one reduces a measure of infeasibility, while in the second the objective function value is reduced.
Aldina Correia, João Matias, Pedro Mestre, Carlos Serôdio   +3 more
openaire   +2 more sources

Curvature-Aware Derivative-Free Optimization

Journal of Scientific Computing
The paper discusses derivative-free optimization (DFO), which involves minimizing a function without access to gradients or directional derivatives, only function evaluations. Classical DFO methods, which mimic gradient-based methods, such as Nelder-Mead and direct search have limited scalability for high-dimensional problems. Zeroth-order methods have
Bumsu Kim, Daniel McKenzie, HanQin Cai, Wotao Yin   +3 more
openaire   +2 more sources

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

A Hybrid Stochastic Deterministic Algorithm for Solving Unconstrained Optimization Problems

Mathematics, 2022
In this paper, a new deterministic method is proposed. This method depends on presenting (suggesting) some modifications to existing parameters of some conjugate gradient methods.
Ahmad M. Alshamrani, Adel Fahad Alrasheedi, Khalid Abdulaziz Alnowibet, Salem Mahdi, Ali Wagdy Mohamed   +4 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Constrained derivative-free optimization on thin domains [PDF]

Journal of Global Optimization, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
José Mario Martínez, F. N. C. Sobral
openaire   +2 more sources

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Improving derivative-free optimization algorithms through an adaptive sampling procedure

Results in Control and Optimization
Black-box optimization plays a pivotal role in addressing complex real-world problems where the underlying mathematical model is unknown or expensive to evaluate.
Emmanouil Karantoumanis, Nikolaos Ploskas   +1 more
doaj   +1 more source