Results 51 to 60 of about 66,063 (262)
Exploring the Direct and Indirect Use of ICT Measurements in DODME (Dynamic OD Matrix Estimation)
Applied Sciences, 2021 The estimation of the network traffic state, its likely short-term evolution, the prediction of the expected travel times in a network, and the role that mobility patterns play in transport modeling is usually based on dynamic traffic models, whose main ...
Xavier Ros-Roca +2 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Fast Well Control Optimization with Two-Stage Proxy Modeling
Energies, 2023 Waterflooding is one of the methods used for increased hydrocarbon production. Waterflooding optimization can be computationally prohibitive if the reservoir model or the optimization problem is complex.
Cuthbert Shang Wui Ng +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
A Second-Order Finite-Difference Method for Derivative-Free Optimization
Journal of MathematicsIn this paper, a second-order finite-difference method is proposed for finding the second-order stationary point of derivative-free nonconvex unconstrained optimization problems.
Qian Chen, Peng Wang, Detong Zhu
doaj +1 more source
Acoustic Sensor Planning for Gunshot Location in National Parks: A Pareto Front Approach
Sensors, 2009 In this paper, we propose a solution for gunshot location in national parks. In Spain there are agencies such as SEPRONA that fight against poaching with considerable success.
Felipe Gil-Castiñeira +7 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
A Derivative-Free Geometric Algorithm for Optimization on a Sphere
CSIAM Transactions on Applied Mathematics, 2020 Summary: Optimization on a unit sphere finds crucial applications in science and engineering. However, derivatives of the objective function may be difficult to compute or corrupted by noises, or even not available in many applications. Hence, we propose a Derivative-Free Geometric Algorithm (DFGA) which, to the best of our knowledge, is the first ...
Chen, Yannan, Xi, Min, Zhang, Hongchao
openaire +3 more sources