Results 61 to 70 of about 66,063 (262)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Annals of the West University of Timisoara: Mathematics and Computer Science, 2016 The paper presents the experimental results of some tests conducted with the purpose to gradually and cumulatively improve the classical DE scheme in both efficiency and success rate. The modifications consisted in the randomization of the scaling factor
Anescu George
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A derivative-free comirror algorithm for convex optimization [PDF]
Optimization Methods and Software, 2014 We consider the minimization of a nonsmooth convex function over a compact convex set subject to a nonsmooth convex constraint. We work in the setting of derivative-free optimization DFO, assuming that the objective and constraint functions are available through a black-box that provides function values for lower- representation of the functions ...
Heinz H. Bauschke +2 more
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
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The Optimal Shape Parameter for the Least Squares Approximation Based on the Radial Basis Function
Mathematics, 2020 The radial basis function (RBF) is a class of approximation functions commonly used in interpolation and least squares. The RBF is especially suitable for scattered data approximation and high dimensional function approximation.
Sanpeng Zheng +2 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
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Conquering the Worst Case of Infections in Networks
IEEE Access, 2020 We develop algorithms to control the scope of an infection spread on a network by allocating a fixed immunization budget to edges of the graph. We assume that the infection propagates according to an independent cascade model and interventions operate by
Wen Yan +4 more
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Derivative-free robust optimization by outer approximations
Mathematical Programming, 2018 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Matt Menickelly, Stefan M. Wild
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
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Nihon Kikai Gakkai ronbunshu, 2014 This paper describes a parameter-free free-form optimization method for shell structures to reduce the noise in a closed acoustic field. Squared sound pressure, which is evaluated by solving fully coupled shell-acoustic interaction system, is selected as
Masatoshi SHIMODA, Kensuke SHIMOIDE
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