Results 51 to 60 of about 21,039 (262)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

DEVELOPMENT OF DERIVATIVE MARKET IN 2000-2012

open access: yesVestnik MGIMO-Universiteta, 2014
At the end of XIX century futures exchange emerged, in the early 70-ies XX century - option exchange of financial derivatives. These exchanges gave a huge boost to the development of market of the operations with derivative financial instruments. In fact,
Evgeniya V. Vasina
doaj   +5 more sources

Do Derivatives Instruments Ownership Decrease Firm Value in Indonesia?

open access: yesRiset Akuntansi dan Keuangan Indonesia, 2020
This research aims to examine the association between derivatives instruments and firm value. This research is quantitative research with multiple linear regression models and panel data.
Amrie Firmansyah, Eko Bayu Dian Purnama
doaj   +1 more source

Futures contracts as a means of hedging market risks

open access: yesAiBi Revista de Investigación, Administración e Ingeniería, 2023
This academic article examines derivative instruments, their role in financial markets, and the associated risks. Derivatives, such as options, forward contracts, and futures, have gained increasing popularity due to their potential for hedging, market ...
Andrés Jerónimo Arenas-Falótico   +1 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

FINANCIAL FUNCTION GUIDANCE IN RISK MANAGEMENT

open access: yesActa Economica, 2005
Financial policy represents the guidance for decision-making process about fundamental financial goals in a company. We accomplish it with the financial management. One of financial functions goals is financial risk exposure reduction.
Jožko Peterlin, PhD
doaj  

FINANCIAL ANALYSIS FOR TRANSACTION WITH FINANCIAL TOOLS AT OMV PETROM CITY ROMANIA [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2017
Through this paper the authors approach the sphere of financial instruments on the capital market. Their conceptual evolution is influenced by both the relationship between the accounting and financial approach and the degree of use for financial ...
ILIE RĂSCOLEAN, ILEANA-SORINA RAKOS
doaj  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Swaps and financial derivatives: risks and returns

open access: yesPSL Quarterly Review, 2013
Derivative financial products have experienced a huge expansion during recent years. New products are constantly appearing which seek to expand the scope of risk diversification.
R.S. MASERA
doaj   +1 more source

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