Results 101 to 110 of about 264,051 (290)

Locating Transition States by Variational Reaction Path Optimization with an Energy-Derivative-Free Objective Function

open access: yes
Locating transition states is essential for understanding molecular reactions. We propose a double-ended transition state search method by revisiting a variational reaction path optimization method known as the MaxFlux method.
Shinji Saito (223594)   +1 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Measurement of free water in foods by secondary derivative thermogravimetry

open access: yesCyTA - Journal of Food, 2018
The thermogravimetry (TGA) and derivative thermogravimetry (DTG) methods have been used to measure the free water in low-moisture foods. In this study, the 2nd derivative thermogravimetry (2nd DTG) method distinguished the free and bound water based on ...
Yubin Wang   +5 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

A derivative-free optimization method for solving classification problem

open access: yes, 2010
Problem statement: The aim of data classification is to establish rules for the classification of some observations assuming that we have a database, which includes of at least two classes. There is a training set for each class.
Abu Hassan, Malik   +2 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The Second-Order Shape Derivative of Kohn–Vogelius-Type Cost Functional Using the Boundary Differentiation Approach

open access: yesMathematics, 2014
A shape optimization method is used to study the exterior Bernoulli free boundaryproblem. We minimize the Kohn–Vogelius-type cost functional over a class of admissibledomains subject to two boundary value problems. The first-order shape derivative of the
Jerico B. Bacani, Gunther Peichl
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Optimal Fourth-Order Methods for Multiple Zeros: Design, Convergence Analysis and Applications

open access: yesAxioms
Nonlinear equations are frequently encountered in many areas of applied science and engineering, and they require efficient numerical methods to solve. To ensure quick and precise root approximation, this study presents derivative-free iterative methods ...
Sunil Kumar   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy