Results 41 to 50 of about 14,414,832 (247)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk   +10 more
wiley   +1 more source

An inexact restoration derivative-free filter method for nonlinear programming [PDF]

open access: yes, 2020
An inexact restoration derivative-free filter method for nonlinear programming is introduced in this paper. Each iteration is composed of a restoration phase, which reduces a measure of infeasibility, and an optimization phase, which reduces the ...
Vignau, Raúl Pedro   +2 more
core  

A Modified Steffensen Iterative Method with Fourth-order Convergence

open access: yesJournal of Harbin University of Science and Technology, 2017
A new fourth-order convergent iterative method formed by Newton’s method and Steffensen method is presented to solve nonlinear equations in this paper. The new iteration formula uses derivative of quadratic interpolation as substitute for derivative of
WEI Jia, HUANG Jia-yue
doaj   +1 more source

A New Generalized Fractional-Order Derivative and Bifurcation Analysis of Cholera and Human Immunodeficiency Co-Infection Dynamic Transmission

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2022
In this study, the co-infection of HIV and cholera model has been developed and analyzed. The new fractional-order derivative is applied and the behavior of the solution is interpreted. The order of new generalized fractional-order derivative implication
Kumama Regassa Cheneke   +2 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman   +9 more
wiley   +1 more source

Chemotherapy for Spinal Cord Intramedullary Pediatric Low‐Grade Glioma—A Systematic Literature Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric intramedullary low‐grade gliomas (PIMLGGs) are rare neoplasms that present unique clinical and management challenges. Although surgery remains the primary tool for tissue diagnosis and decompression, complete gross‐total resection is frequently unfeasible due to the infiltrative nature of these lesions.
Olga M. Sergeenko   +5 more
wiley   +1 more source

An optimal eighth order derivative free multiple root finding numerical method and applications to chemistry [PDF]

open access: yes, 2023
[EN] In this paper, we present an optimal eighth order derivative-free family of methods for multiple roots which is based on the first order divided difference and weight functions.
Fiza Zafar   +3 more
core   +1 more source

Derivative-free neural network for optimizing the scoring functions associated with dynamic programming of pairwise-profile alignment

open access: yesAlgorithms for Molecular Biology, 2018
Background A profile-comparison method with position-specific scoring matrix (PSSM) is among the most accurate alignment methods. Currently, cosine similarity and correlation coefficients are used as scoring functions of dynamic programming to calculate ...
Kazunori D. Yamada
doaj   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

On a New Method for Derivative Free Optimization [PDF]

open access: yes, 2011
A new derivative-free optimization method for unconstrained optimization of partially separable functions is presented. Using average curvature information computed from sampled function values the method generates an average Hessian-like matrix and uses
Frimannslund, Lennart, Steihaug, Trond
core  

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