Results 181 to 190 of about 1,196,568 (318)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Some Landau Type Inequalities for Functions whose Derivatives are of locally bounded variation

open access: yes, 2005
Some inequalities of the Landau type for functions whose derivatives are of locally bounded variation are pointed ...
Dragomir, Sever S, Barnett, Neil S
core  

Novel sugar-conjugated Knoevenagel condensate curcumin derivatives as promising bioactive hybrids with antimalarial potential. [PDF]

open access: yesRSC Adv
Jamil SNH   +9 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The Determinants of Financial Derivatives Use in the UK life Insurance Industry

open access: yes, 1999
This paper examines the determinants of financial derivatives use in the United Kingdom (UK) life insurance industry. We estimate a probit regression model and a Heckman two-stage sample selection regression model using a sample of 88 UK life insurers
Hardwick, Philip, Adams, Mike
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The Impact of Institutional Differences on Derivatives Usage: A Comparative Study of US and Dutch Firms

open access: yes
This paper tests the influence of institutional differences on risk management practices.Several survey studies have investigated derivatives usage for risk management purposes in the US (see, among others, Bodnar, Hayt, Marston and Smithson, 1995 and ...
Jong, A. de, Macrae, V., Bodnar, G.M.
core  

Currency Derivatives under a Minimal Market Model with Random Scaling [PDF]

open access: yes
This paper uses an alternative, parsimonious stochastic volatility model to describe the dynamics of a currency market for the pricing and hedging of derivatives.
David Heath, Eckhard Platen
core  

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