Results 51 to 60 of about 335,006 (216)

Phylogenetic and Genetic Variation Analysis of Porcine Epidemic Diarrhea Virus in East Central China during 2020–2023

Animals
Porcine epidemic diarrhea virus (PEDV) is a major causative pathogen of a highly contagious, acute enteric viral disease. This study evaluated the emergence of nine variants in Jiangsu and Anhui provinces of China from 2020 to 2023.
Liumei Sun, Duo Li, Caijie Yan, Chengyue Wu, Feng Han, Zongyi Bo, Manman Shen, Yiwei Sun, Liyan Wang, Haoqin Zheng, Mengdong Wang, Zhendong Zhang   +11 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Transcranial magnetic stimulation-based evaluation of exercise training-induced changes in TMS-derived neurophysiological markers and motor performance in healthy adults: a systematic review and meta-analysis of RCTs

Frontiers in Neurology
BackgroundTranscranial magnetic stimulation (TMS) is a well-established, non-invasive technique for assessing motor cortical and corticospinal function, including corticospinal excitability and intracortical inhibition/facilitation. Because commonly used
Yili Gao, Yili Gao, Ziwen Zhen, Juanjuan Hu   +3 more
doaj   +1 more source

SCS453 Noninha and SCS454 Carvoeira – new banana cultivars of the Prata subgroup

Crop Breeding and Applied Biotechnology, 2023
‘SCS453 Noninha’ and ‘SCS454 Carvoeira’ are new banana cultivars derived from the subgroup Prata (AAB). In comparison with the latter, ‘SCS453 Noninha’ has a low pseudostem height, ‘SCS454 Carvoeira’ a high yield and both unchanged fruit characteristics.
Ramon Felipe Scherer, André Boldrin Beltrame, Gustavo Henrique Ferrero Klabunde, Luana Aparecida Castilho Maro, Gelton Geraldo Fernandes Guimarães, Márcio Sônego, Luiz Alberto Lichtemberg   +6 more
doaj  

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

How can latent trajectories of back pain be translated into defined subgroups?

BMC Musculoskeletal Disorders, 2017
Background Similar types of trajectory patterns have been identified by Latent Class Analyses (LCA) across multiple low back pain (LBP) cohorts, but these patterns are impractical to apply to new cohorts or individual patients.
Alice Kongsted, Lise Hestbæk, Peter Kent   +2 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

MRI and Ultrasound of the Thoracolumbar Fascia in the Setting of Degenerative Spinal Diseases

Medicina
Background and Objectives: The thoracolumbar fascia (TLF) has been implicated in low back pain, but imaging-based characterization in degenerative lumbar disorders, particularly in surgical cohorts, remains limited. To describe MRI-derived and US-derived
Noa Martonovich, Clara De Luca, Caterina Fede, Andrea Angelini, Pietro Ruggieri, Eyal Behrbalk, Carla Stecco, Carmelo Pirri   +7 more
doaj   +1 more source