Results 91 to 100 of about 1,062,941 (282)

A Novel Workflow for Non-Animal PBK Modelling of UV Filters: Oxybenzone as a Case Study

open access: yesPharmaceuticals
Background/Objectives: Physiologically based kinetics (PBK) modelling provides (internal) exposure concentrations. We used a PBK model parameterized exclusively with in silico and in vitro data in a bottom-up approach to predict the pharmacokinetics of ...
Nazanin Golbamaki   +7 more
doaj   +1 more source

In vitro modelling of dermal absorption of chemicals following environmental or accidental exposure [PDF]

open access: yes, 2010
These studies were aimed at identifying potential surrogate compounds for dermal absorption of bioactive agents in vitro using flow through and static cell diffusion systems, and also to generate novel data on the effects of application vehicle on ...
Moore, Craig Andrew
core  

In silico model to predict dermal absorption of chemicals in finite dose conditions [PDF]

open access: yes
The development of in silico approaches that can estimate the dermal absorption of chemicals exposed in practical conditions is highly anticipated. In the present study, an in silico model to estimate both the dermal absorption rate and dermal permeation
杉林, 堅次   +8 more
core   +1 more source

Autonomous Reconfigurable Modular Conductive Hydrogels for Adaptive and Degradable Bioelectronic Interfaces

open access: yesAdvanced Materials Technologies, EarlyView.
Bridging rigid electrodes with soft, irregular tissues demands more than conductivity alone. Modular conductive hydrogels autonomously reconfigure into conformal electrode‐tissue interfaces, coupling mixed ionic‐electronic conduction with tissue‐like mechanics, self‐healing, and degradability.
Matthew K. Burgess   +4 more
wiley   +1 more source

Assessment of the health risks of some potentially toxic elements’ (PTEs) intake via soil particles from a grassless sports facility in Abakaliki, Ebonyi State, Nigeria

open access: yesDiscover Environment
The concentrations of some PTEs in soils from a grassless sports facility in Abakaliki, Ebonyi State, were assessed to predict the health risks that may be associated with their intake as particles through inhalation and dermal absorption.
Godwin Nkwuda Nwonumara   +4 more
doaj   +1 more source

Radiofrequency Microneedling-Mediated Enhancement in Percutaneous Delivery of Topical Triamcinolone Acetonide: An In Vivo Quantitative Study

open access: yesLife
Background: The stratum corneum (SC) limits the efficacy of topical corticosteroids. Radiofrequency microneedling (RFMN) may enhance drug delivery; however, quantitative in vivo human data remain limited.
Rosalyn Kupwiwat   +7 more
doaj   +1 more source

3D Printing of Self‐Healing Polymers by Material Extrusion: A Process‐Centric Review of Setups, Parameters, and Applications

open access: yesAdvanced Robotics Research, EarlyView.
This review highlights recent advances in material extrusion 3D printing of self‐healing polymers, focusing on the interplay between material chemistry, rheology, hardware customization, and process optimization. Filament‐ and ink‐based extrusion strategies, multimaterial architectures, and postprocessing approaches are discussed for applications in ...
Antonio Pavone   +2 more
wiley   +1 more source

Comparison of international guidelines of dermal absorption tests used in pesticides exposure assessment for operators

open access: yes, 2014
The number of farmers who have suffered from non-fatal acute pesticide poisoning has been reported to vary from 5.7% to 86.7% in South Korea since 1975. Absorption through the skin is the main route of exposure to pesticides for farmers who operate with ...
So, Jaehwan   +7 more
core   +1 more source

Wireless Precise Manipulation of Tumor Spheroids Using a Millirobot Controlled by Permanent Magnetic Traps

open access: yesAdvanced Robotics Research, EarlyView.
A magnetic donut‐like millirobot is developed for label‐free pick‐and‐place of a tumor spheroid wirelessly controlled by a magnetic trap. Spheroids are important 3D multicellular culture systems that recapitulate key structural and functional features of native tissues.
Yue Gao   +8 more
wiley   +1 more source

Skin permeability and pharmacokinetics of diclofenac epolamine administered by dermal patch in Yorkshire-Landrace pigs

open access: yesJournal of Pain Research, 2012
Susanna Tse,1 Kendall D Powell,2 Stephen MacLennan,3 Allan R Moorman,4 Craig Paterson,5 Rosonald R Bell11Pfizer Inc, Groton, CT, USA; 2Tandem Labs, Durham, NC, USA; 3BioCryst Pharmaceuticals Inc, Durham, NC, USA; 4Alta Vetta Pharmaceutical Consulting LLC,
Tse S   +5 more
doaj  

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