Results 81 to 90 of about 1,910,776 (311)

The toxicity of cadmium and resulting hazards for human health [PDF]

, 2006
Cadmium (Cd) has been in industrial use for a long period of time. Its serious toxicity moved into scientific focus during the middle of the last century.
David A Groneberg, Scheidig, Franziska, Groneberg, Jan David Alexander, Franziska Scheidig, Godt, Johannes, Esche, Vera, Johannes Godt, Paul Brandenburg, Christian Grosse-Siestrup, Reich, Andrea, Brandenburg, Paul, Andrea Reich, Vera Esche, Grosse-Siestrup, Christian   +13 more
core   +1 more source

Mimetic Core‐Sheath Silk Sutures with Superior‐Strength for Pain Management, Anti‐Infection and Wound Healing

Advanced Healthcare Materials, EarlyView.
ABSTRACT Sutures are crucial for tissue approximation and wound healing. Besides their strength limits requirement, they often fail to effectively address complications like infection and pain. Inspired by natural silk's “core‐sheath” structure, our suture features a wet‐spun core of n zinc‐fortified silk fibroin fibers (RSF‐Zn2+) after drawing with ...
Yi Peng, Kai Ma, Xiaoxiao Li, Xiaozhuo Wu, Yuezhou Zhang, Ying Luo, Chenxing Zhang, Wen Zhong, Chunjing Yu, Lin Lu, Malcolm Xing, Guozhong Lyu   +11 more
wiley   +1 more source

Prediction of concentration-time profile and its inter-individual variability following the dermal drug absorption [PDF]

, 2012
Estimation of systemic exposure after absorption of any xenobiotic from the skin is very important in development of dermal pharmaceutical products as well as assessing un-intended exposures due to cosmetic products or environmental and occupational ...
Rostami-Hodjegan, Amin, Ahamadi, Malidi, Mishra, Himanshu, Ghobadi, Cyrus, Patel, Nikunjkumar, Jamei, Masoud, Polak, Sebastian   +6 more
core   +1 more source

Percutaneous Absorption of Fireground Contaminants: Naphthalene, Phenanthrene, and Benzo[a]pyrene in Porcine Skin in an Artificial Sweat Vehicle

Toxics
Firefighters face significant risks of exposure to toxic chemicals, such as polycyclic aromatic hydrocarbons (PAHs), during fire suppression activities.
Chandler Probert, Emma Nixon, R. Bryan Ormond, Ronald Baynes   +3 more
doaj   +1 more source

Dermal absorption of aromatic amines in workers with different skin lesions: a report on 4 cases

Journal of Occupational Medicine and Toxicology, 2006
There are only few studies about the relationship of skin lesions and the percutaneous uptake of hazardous substances in exposed workers. Several aromatic amines are well known carcinogens for humans and/or animals.
Angerer Jürgen, Weiss Tobias, Korinth Gintautas, Drexler Hans   +3 more
doaj   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source

Refinement and enhancement of a database for dermal absorption data [PDF]

, 2022
S.S90, Abstract 361Dermal absorption is an important factor in regulatory science regarding the registration of chemicals, agrochemicals and cosmetics.
Genth, H., Schmeinck, Sina, Bitsch, Annette   +2 more
core  

Skin Permeability of Perfluorocarboxylic Acids Using Flow-Through Diffusion on Porcine Skin

Toxics
Per- and polyfluoroalkyl substances (PFAS) are found in a variety of places including cosmetics, rain jackets, dust, and water. PFAS have also been applied to occupational gear to protect against water and oils.
Andrew Stephen Hall, Ronald Baynes, Laura M. Neumann, Howard I. Maibach, R. Bryan Ormond   +4 more
doaj   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

A Novel Perfused Full‐Thickness Human Skin Microphysiological System for Modeling Injury, Regeneration, Tumor Pathophysiology, and Therapeutics Development

Advanced Healthcare Materials, EarlyView.
What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu, Hamid Malekzadeh, Alexa Rivera Del Rio Hernandez, Naresh Mahajan, Ethan Banks, Dayyan Ur Rahman, José A. Arellano, Katherine S. Yang, Alexey Altman, G.V. Naveen Kumar, Matthew L. Steinhauser, Jeffrey A. Gusenoff, J. Peter Rubin, Asim Ejaz   +13 more
wiley   +1 more source