Results 211 to 220 of about 281,777 (272)

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li   +8 more
wiley   +1 more source

Adult-onset hypopigmented mycosis fungoides: CD8-predominant presentation beyond the classic patch. [PDF]

open access: yesJAAD Case Rep
Farishta A   +5 more
europepmc   +1 more source

A Single‐Amino‐Acid Ligand for LAT1: A Minimalist and Modular Platform for Lysosome‐Targeted Degradation of Membrane Proteins

open access: yesAdvanced Science, EarlyView.
LA‐LYTAC repurposes the cancer‐enriched amino acid transporter LAT1 as a lysosomal trafficking receptor for targeted membrane‐protein degradation. A single phenylalanine‐derived ligand, modularly linked to antibodies or small‐molecule binders, recruits PD‐L1, EGFR, or integrins to LAT1, triggering transporter‐mediated internalization, lysosomal ...
Liquan Zhu   +12 more
wiley   +1 more source

Interference of ATP‐Binding Cassette Transporter by Functional Nano‐Delivery System for High Efficiency Management of Insecticide‐Resistant Nilaparvata lugens

open access: yesAdvanced Science, EarlyView.
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He   +9 more
wiley   +1 more source

A 3D-Printed Scaffolded Hydrogel Microneedle Array Biosensor for Real-Time, Continuous Monitoring. [PDF]

open access: yesAdv Mater
Kwak JW   +20 more
europepmc   +1 more source

Reinforced Repair of Urethrovaginal Fistula Using Bovine Pericardial Patch. [PDF]

open access: yesJ Indian Assoc Pediatr Surg
Rakhesh M   +4 more
europepmc   +1 more source

Microneedle-Mediated Delivery of Extracellular Matrix-Inspired Peptides for Mitigation of Burn Wound Progression and Support of Tissue Repair. [PDF]

open access: yesWound Repair Regen
Dos Santos DM   +7 more
europepmc   +1 more source

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