Results 131 to 140 of about 128,590 (274)

Erythematous Papules and Plaques in an Infant Receiving Glucagon Therapy

JEADV Clinical Practice, EarlyView.
Sara Al Janahi, Alya Al‐Ali, Meera Al Adawi, Yusra S. Al Ali, Harish Bangalore   +4 more
wiley   +1 more source

Allergic Contact Dermatitis: A Comparative Study of Elderly and Young Over Time

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Delayed hypersensitivity reactions, such as allergic contact dermatitis (ACD), present distinct patterns across age groups. While age‐related immune changes are well‐documented, their impact on patch test outcomes and allergen sensitization in elderly individuals remains underexplored.
Roberto Mazzetto, Emma Soldi, Laura Ventura, Ludovica Deotto, Francesca Caroppo, Anna Belloni Fortina   +5 more
wiley   +1 more source

Reduction of Rescue Treatment With Dupilumab for Chronic Rhinosinusitis With Nasal Polyps in Japan

The Laryngoscope, EarlyView.
This observational study examined the impact of add‐on dupilumab treatment on the use of rescue therapy in Japanese individuals with chronic rhinosinusitis with nasal polyps (CRSwNPs) using data from a large hospital‐based administrative claims database.
Mamoru Yoshikawa, Mitsuhiro Okano, Makiko Takeuchi, Yoshinori Sunaga, Mami Orimo, Masato Ishida   +5 more
wiley   +1 more source

Investigating Airway Symptoms in Eosinophilic Esophagitis (EoE)

The Laryngoscope, EarlyView.
ABSTRACT Objectives Diagnostic delay of eosinophilic esophagitis (EoE) is significant, and efforts are needed to raise awareness and reduce prolonged symptoms and complications. Airway and swallowing symptoms often overlap, especially in children, complicating diagnosis and increasing delays.
Angela Huynh, Amanda Adsett, Amy Callaghan, Hien Q. Huynh, Hamdy El‐Hakim, André Isaac, Daniela M. Isaac   +6 more
wiley   +1 more source

Feasibility of Treating Eosinophilic Chronic Rhinosinusitis Using Short‐Chain Fatty Acids

The Laryngoscope, EarlyView.
Epithelial cell‐derived cytokines including thymic stromal lymphopoietin (TSLP) are important in the pathogenesis of chronic rhinosinusitis with nasal polyps. We demonstrate the inhibitory effect of TSLP production in airway epithelial cells and eosinophil survival by short‐chain fatty acids (SCFAs) as a potential new strategy to reduce nasal polyps ...
Rikako Gozawa, Yoshimasa Imoto, Yuki Sonoda, Ayako Maegawa, Anna Shimizu, Masanori Kidoguchi, Keisuke Koyama, Naoto Adachi, Taiyo Morikawa, Yuto Miyazaki, Kyoko Saito, Masafumi Sakashita, Shigeharu Fujieda   +12 more
wiley   +1 more source

Dermoscopic Evaluation of Erythema Versus Post‐Inflammatory Hyperpigmentation (PIH) in Skin of Color (SOC) Patients

JEADV Clinical Practice, EarlyView.
Shirley P. Parraga, Tiffany T. Mayo
wiley   +1 more source

Guideline for the diagnosis, treatment, and prevention of respiratory syncytial virus infection in children in China

Pediatric Investigation, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is one of the most common respiratory pathogens in children under 5 years of age worldwide and it seriously threatens children's health. In recent years, great progress has been made in the field of RSV‐related diseases.
Committee of Pediatrics, China Medical Education Association, Subspecialty Group of Respiratory Diseases, Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of China Non‐public Medical Institution Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China Medical News and Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, Global Pediatric Respiratory Alliance, Beijing Hairun Charity Foundation   +16 more
wiley   +1 more source

Semi‐Mechanistic Population Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling of Dupilumab on Pre‐Bronchodilator Forced Expiratory Volume in 1 Second (FEV1) in Uncontrolled Moderate‐To‐Severe Asthma

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT In this study, we investigated the pharmacokinetic/pharmacodynamic (PK/PD) relationship of dupilumab as an add‐on therapy in the intent‐to‐treat (ITT) uncontrolled moderate‐to‐severe asthma population and identified the factors significantly contributing to variability in forced expiratory volume in 1 second; (FEV1).
Li Zhang, John D. Davis, Vanaja Kanamaluru, Christine Xu   +3 more
wiley   +1 more source

Continuous‐Time Markov Population PK/PD Modeling of Longitudinal EASI Categorical Score in Atopic Dermatitis Treated With Rocatinlimab, an Anti‐OX40 Monoclonal Antibody

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Rocatinlimab (AMG 451/KHK4083) is a potential T‐cell rebalancing therapy that inhibits and reduces the number of pathogenic T cells by targeting the OX40 receptor; it is associated with a progressive and sustained response for patients with moderate‐to‐severe atopic dermatitis (AD).
Hiroki Okada, Sam Liao, Lisa Khouri, Lori Liao, Matthew W. Hruska, Yoshinori Nagata, Maki Hasegawa, Andrew Gewitz, Douglas Marsteller   +8 more
wiley   +1 more source

Synthesis of Boronic Acid‐Functionalized Core–Shell Mesoporous Silica–TiO2 Nanocomposite for Specific Enrichment of Glycopeptides From Biological Samples

Small Methods, EarlyView.
The schematic illustrates a workflow showing the current investigation using a boronic acid‐functionalized core–shell mesoporous silica‐TiO₂ (CSMS@TiO₂‐GLYMO‐APB) for N‐glycopeptide enrichment from biological samples, involving trypsin digestion, enrichment, deglycosylation with PNGase F, and subsequent mass spectrometry (MALDI‐TOF MS and Nano‐LC‐MS/MS)
Mohamed Adly Gab‐Allah, Maryam Adelipour, Hyojin Hwang, Reham M. Marzouk, Heejin Lim, Jooyeon Oh, Ji‐Hyun Cha, Jaebeom Lee, Jeongkwon Kim   +8 more
wiley   +1 more source