Real-world Efficacy and Safety of Stapokibart in Children and Adolescents with Moderate-to-severe Atopic Dermatitis: A Retrospective Study. [PDF]
Li L +9 more
europepmc +1 more source
The SENDO cohort study (2015–2024) prospectively analyzed the impact of ultra‐processed food (UPF) consumption on asthma and atopy in 1,546 Spanish children. Higher UPF intake (NOVA 4 classification) was significantly associated with an increased risk of asthma but not atopy, atopic dermatitis, neumoallergen sensitation, food allergy over five years ...
O. Galindo +6 more
wiley +1 more source
Atopic Dermatitis in Children: Differential Diagnosis and Mimickers. [PDF]
Türe Avcı B +3 more
europepmc +1 more source
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton +19 more
wiley +1 more source
Pregnancy in Women with Atopic Dermatitis: A Systematic Review of Concerns and Challenges. [PDF]
Nørreslet LB, Agner T, Mortz CG.
europepmc +1 more source
MAIT Cells Suppress IgE‐Mediated Asthma via IFNγ‐Dependent B Cell Regulation
In this study, we demonstrate that MAIT cell antagonism during sensitization and challenge with HDM worsens the development of airway hyperreactivity without effects on type 2 or 17 associated cytokine production or lung inflammation. Rather, MAIT cells appear to regulate HDM‐induced asthma through direct inhibition of IgE production.
Angela M. Cannata +6 more
wiley +1 more source
Psoriasis, Atopic Dermatitis, Acne, Inverse Psoriasis and Hidradenitis: A Case Report of Multiple Disease in a Same Young Patient. [PDF]
Amore E +4 more
europepmc +1 more source
Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma
EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler +22 more
wiley +1 more source
Atopic Dermatitis Across the Lifespan: Understanding, Measuring and Minimizing Cumulative Life Course Impairment. [PDF]
Augustin M +7 more
europepmc +1 more source
Keratinocyte Priming by Staphylococcus aureus Reduces HSV‐1 Susceptibility
ADEH+ patients have a reduced microbial diversity with increased S. aureus and S. epidermidis colonization compared to ADEH− and healthy controls. Heat‐killed S. aureus reduced HSV‐1 susceptibility and release of infectious progeny virus in a keratinocyte in vitro model. Heat‐killed S.
Phila Cara Baumann +19 more
wiley +1 more source

