Results 171 to 180 of about 166,203 (279)

Case Report: Effective IL-4/IL-13 axis suppression and resolution of severe atopic dermatitis by dupilumab monotherapy in a patient with IPEX syndrome. [PDF]

Front Immunol
Alshanti M, MacDougall MS, Gokbak MN, Ramachandran A, Alzaabi AA, Alexander JL, Bacchetta R, Shendi HM.   +7 more
europepmc   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Sleep Disturbance and Atopic Dermatitis: A Bidirectional Relationship With Clinical and Therapeutic Implications. [PDF]

Cureus
Kaliciak I, Korda O.
europepmc   +1 more source

Dendritic Cell α‐Ketoglutarate Regulates Tfh Polarization in Allergy

Allergy, EarlyView.
Allergen induces a dendritic cell metabolism shift toward glutaminolysis with α‐ketoglutarate as a regulator of Tfh subset polarization. Glutaminolysis is required for DC allergen uptake, co‐stimulatory molecule expression, and CLR expression. Modulation of glutaminolysis, JmjD3 histone demethylation, or HIF‐1α degradation alters Tfh polarization and ...
Anuj Tharakan, Xufeng Qu, Carmen Camarena, Araba Abaidoo‐Myles, Parth Naik, Jeremy Allegood, Ankit Kumar, Mihir Pokhriyal, Joseph C. Lownik, Matthew P. Zellner, Grayson W. Way, Jinze Liu, Lauren Ashley Cowart, Stephanie C. Eisenbarth, Joseph W. Landry, Daniel H. Conrad, Rebecca K. Martin   +16 more
wiley   +1 more source

Defining prevalence of atopic dermatitis in the Avon Longitudinal Study of Parents and Children (ALSPAC). [PDF]

Wellcome Open Res
Ye M, Langan SM, Abuabara K.
europepmc   +1 more source

Family Size and Food Allergy in Early Childhood: The Japan Environment and Children's Study

Allergy, EarlyView.
Takayasu Nomura, Hisashi Tanida, Takeshi Inoue, Sayaka Kato, Daiki Hiraoka, Yuki Ito, Mayumi Sugiura‐Ogasawara, Shinji Saitoh, Michihiro Kamijima, Yukihiro Ohya, The Japan Environment and Children's Study (JECS) Group, Michihiro Kamijima, Shin Yamazaki, Maki Fukami, Reiko Kishi, Chiharu Ota, Koichi Hashimoto, Kenichi Sakurai, Shuichi Ito, Ryoji Shinohara, Hidekuni Inadera, Takeo Nakayama, Ryo Kawasaki, Yasuhiro Takeshima, Hideki Nagashima, Narufumi Suganuma, Mayumi Tsuji, Kimitoshi Nakamura   +27 more
wiley   +1 more source

Microbiota Signatures in Early Life and Their Association With Food Allergy: A Systematic Review

Allergy, EarlyView.
ABSTRACT Food allergy (FA) is increasing worldwide, and early life may be a critical window for immune training. We systematically reviewed observational human studies linking early‐life microbiota (infant, maternal, environmental, or extraintestinal) profiled using culture‐based and/or culture‐independent methods (including sequencing‐based approaches)
Eduard Flores Ventura, Jeremy Corriger, Hélène Omer, Marie Bodinier, Dirk Haller, Tomer Hertz, Martin Larsen, Maria Carmen Collado   +7 more
wiley   +1 more source

Stapokibart for Facial-Predominant AD-Like Dermatoses: A Retrospective Real-World Case Series Highlighting Response Heterogeneity. [PDF]

Clin Cosmet Investig Dermatol
Zhu Y, Chen J, Wang P, Feng P, Wang X.
europepmc   +1 more source

Maternal Perinatal Gut Microbiome Is Shaped by Traditional Farming Lifestyle and Associated With Early Childhood Atopic Disease

Allergy, EarlyView.
We assessed whether the maternal perinatal gut microbiome and serum SCFA and cord blood SCFA differ between traditional farming and urban dyads. Women following a farming lifestyle had increased microbial diversity, several differentially abundant bacterial species and functional pathways, and increased circulating SCFA. Overall maternal gut microbiome
Erin C. Davis, Courtney M. Jackson, Nichole S. Diaz, Jazmine Susana, Ashley Nelson, Richard Insel, Antti E. Seppo, Kirsi M. Järvinen   +7 more
wiley   +1 more source

Exploring type 2 inflammation and disease complexity: perspectives of a clinical immunologist. [PDF]

Front Immunol
Tal Y, Rubin L, Munitz A, Adini I.
europepmc   +1 more source