Results 161 to 170 of about 166,203 (279)

Innovative paradigms in atopic dermatitis management: a translational lens

The thesis covers various aspects of the disease, including epidemiology, etiology, pathophysiology, classification, clinical features, diagnosis, and management.
Narita, Yuzuha
core  

Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions

Allergy, EarlyView.
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira, Lisa Holla, Sophia Björkander, Marie Kaarup Bek, Lorenz Wirth, Patrick A. Shearer, Jesper Säfholm, Erik Sachs, Mamdoh Al‐Ameri, Kasra Vali, Sandra Ekström, Erik Melén, Jenny Mjösberg, Christopher Andrew Tibbitt   +13 more
wiley   +1 more source

Emollient Formulations and Skin Barrier Practices in the Context of Eczema and Food Allergy Prevention

Allergy, EarlyView.
ABSTRACT The skin is far from a passive shield; it functions as a dynamic “living barrier” whose structural and immunological integrity is paramount in preventing atopic dermatitis (AD) and the subsequent progression of the atopic march toward food allergy (FA).
Klaudia Ryczaj, Donald Y. M. Leung, Carina Venter, Barbara Sozańska, Helen A. Brough   +4 more
wiley   +1 more source

Efficacy and Safety of Dupilumab in Chinese Adult Patients With Chronic Rhinosinusitis With Nasal Polyps: A Randomized, Placebo‐Controlled, Phase III Trial

Allergy, EarlyView.
Dupilumab significantly improved nasal polyp score, nasal congestion, olfaction, total symptom score, and disease‐specific quality of life in Chinese patients with uncontrolled CRSwNP. Incidence of treatment‐emergent adverse events was similar between dupilumab and placebo.
Mu Xian, Menglin Wang, Changqing Zhao, Lijia Wan, Yu Xu, Juan Meng, Rui Xu, Xicheng Song, Li Shi, Yucheng Yang, Yan Jiang, Yanzhen Wu, Bethany Ling, Vivian Li, Andrew P. Fontenot, Lacey R. Robinson, Neelam A. Phadke, Chengshuo Wang, Luo Zhang   +18 more
wiley   +1 more source

Association between smoking and the clinical status of adult patients with moderate-severe atopic dermatitis in the China Atopic Dermatitis Registry (ChinaSTAD): a cross-sectional study. [PDF]

Front Med (Lausanne)
Yu Y, Cao L, Fan X, Lu L, Wang S, Zhang J, Lin B.   +6 more
europepmc   +1 more source

A Retrospective Review of Scabies Cases Managed by the Dermatology Department in a North Queensland Hospital Over a 10‐Month Period

Australasian Journal of Dermatology, EarlyView.
Madeleine Louise Kelly, Crystal Williams
wiley   +1 more source

Determinants of Poor Health‐Related Quality of Life in Patients With Food Allergy

Allergy, EarlyView.
Machine‐learning analysis of 502 well‐characterised food‐allergic patients was used to identify key determinants of poor FA‐HRQL, defined as FAQLQ ≥ 5. The most relevant predictors were adult age, female sex, multiple food allergies, severe reactions, need for urgent care, onset before 18 years, and longer disease duration.
Rosialzira Natasha Vera‐Berrios, Alejandro Gonzalo‐Fernández, Natalia Freundt‐Serpa, Guadalupe Marco‐Martín, Beatriz Fernández‐Parra, María Isabel Alvarado‐Izquierdo, Rocío Casas‐Saucedo, Cristina Stein‐Coronado, Ethel Ibáñez‐Echevarría, Tania Ramos‐García, María Dolores Alonso‐Díaz de Durana, Azahara López‐Raigada, Carlos Blanco‐Guerra, María Pía de Calzada‐Bustingorri, Teresa Carrillo‐Díaz, Hilda Rianec Hernández‐Suárez, Miguel Ángel Díaz‐Palacios, Sonsoles Infante‐Herrero, Ana María Nieto‐Nieto, Sonia Vázquez‐Cortés, Eloína González‐Mancebo, María M. Escribese, Pilar Rico‐Nieto, Domingo Barber, Montserrat Fernández‐Rivas   +24 more
wiley   +1 more source

The Prevalence, Knowledge, and Awareness Level of Atopic Dermatitis Among a Sample of Adult Jordanian Population. [PDF]

Clin Cosmet Investig Dermatol
Saleh MM, Al-Qerem W, Karaki LA, Al-Zayadneh A, Al-Awawdeh A.   +4 more
europepmc   +1 more source

Development of Nummular Dermatitis Following Dupilumab Therapy Suggests a Th17‐Driven Mechanism

Australasian Journal of Dermatology, EarlyView.
Olga Pawlik, Michelle McRae
wiley   +1 more source

Differential Roles for IL‐4Rα and IL‐13Rα1 in Immune Cell Infiltration and Epithelial Remodeling in Experimental Eosinophilic Gastritis

Allergy, EarlyView.
This study described the development of an experimental model for eosinophilic gastritis (EoG). Experimental EoG recapitulates histopathological features of human disease. including foveolar elongation, fibrosis, eosinophilia, mastocytosis and shared transcriptional programs.
Anish Dsilva, Shraddha Sharma, Shireen Barakey, Ariel Wagner, Alice Keisar, Tali Bar‐on, Michal Itan, Ariel Munitz   +7 more
wiley   +1 more source