Knowledge, Attitudes, and Practices Towards Atopic Dermatitis Among Parents of Children with Atopic Dermatitis: A Cross-Sectional Study. [PDF]
Zheng H +6 more
europepmc +1 more source
Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery +25 more
wiley +1 more source
Efficacy, Safety and Immunomodulatory Effect of Intramuscular Injections of Autologous Whole Blood Into Acupoints in Patients With Atopic Dermatitis: A Randomized Controlled Trial. [PDF]
Li X +10 more
europepmc +1 more source
The Evolution of Sesame Seed Allergy Over Time
This study analyzes the natural history of sesame over time and the changes in biomarkers between sesame allergic and sesame sensitised but tolerant children. The period prevalence of sesame allergy increased from 0.5% between 12 and 36 m to 1.5% between 7 and 12 y children in the EAT‐On study with 10 children developing new sesame allergy. Sesame‐sIgE
Ru‐Xin Foong +14 more
wiley +1 more source
Real-World Treatment Patterns and Determinants of Therapy in Pediatric Atopic Dermatitis: A 10-Year Experience from a Tertiary Referral Center in Thailand. [PDF]
Yusakda N +7 more
europepmc +1 more source
A Case for Anti‐IgE Vaccination
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff +3 more
wiley +1 more source
Dupilumab for Trichothiodystrophy-Case Report and Review of the Literature. [PDF]
O'Mahony J, O'Connor C.
europepmc +1 more source
Application of atopic dermatitis control tool (ADCT) for daily practice in a community-based dermatology clinic. [PDF]
Ebata T, Hayakawa-Ventimiglia Y, Lin Q.
europepmc +1 more source
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud +23 more
wiley +1 more source

