Results 211 to 220 of about 166,203 (279)

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

open access: yesAllergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz   +22 more
wiley   +1 more source

Sodium polyphosphate, a new drug for treatment of atopic dermatitis: basic considerations and clinical case studies.

open access: yesBiomater Sci
Neufurth M   +9 more
europepmc   +1 more source

Spatial Transcriptomics Identifies Characteristic Immunological Niches in Atopic Dermatitis

open access: yesAllergy, EarlyView.
Spatially organized immune niches containing mature migratory dendritic cells (mmDCs) and CD4+ T cells in atopic dermatitis lesions support localized T cell activation and may contribute to disease persistence. Spatial transcriptomics identifies conserved immune niches in atopic dermatitis lesions, characterized by close co‐localization of CD4+ T cells
Lina Gross   +11 more
wiley   +1 more source

IgE Sensitization Patterns of Mothers and Their Offspring in the First Five Years of Life The CHILD Study

open access: yesAllergy, EarlyView.
The spectrum of allergic sensitization in mothers and their offspring was characterized at ages 1–5 years at an extract‐ and molecular level in a North American birth cohort. Fel d 1 was the primary sensitizer in mothers, followed by Phl p 1. Perennial allergen sensitization (Der f 1, Der p 1) was rare at age one but rose sharply by age five.
Mary Asumta Anyango Kodydek   +14 more
wiley   +1 more source

Immune System Development—Pro Tips for Paediatricians

open access: yesActa Paediatrica, EarlyView.
ABSTRACT There are many misconceptions about the immune system in children, its impact on infectious disease susceptibility and its role in the rapidly increasing rates of immune mediated diseases in industrialized societies. In this mini review, I will discuss common believes and the data supporting or countering such believes, with a focus on ...
Petter Brodin
wiley   +1 more source

Safety and Clinical Outcomes of High‐ Versus Low‐Dose Oral Peanut Immunotherapy in Polish Children With Peanut Allergy

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To compare safety and clinical outcomes of two different oral immunotherapy (OIT) maintenance doses (150 mg vs. 300 mg) of peanut protein in children with peanut allergy. Methods This prospective study enrolled 44 children aged 4–17 years with confirmed peanut allergy.
Klementyna Łyżwa   +4 more
wiley   +1 more source

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