Results 41 to 50 of about 304,024 (319)
Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis [PDF]
BackgroundAtopic dermatitis (AD; eczema) is characterized by a widespread abnormality in cutaneous barrier function and propensity to inflammation. Filaggrin is a multifunctional protein and plays a key role in skin barrier formation.
Barton, Geoffrey J.+10 more
core +3 more sources
Update “Systemic treatment of atopic dermatitis” of the S2k‐guideline on atopic dermatitis
This guideline is an update from August 2020 the S2k‐guideline “Atopic dermatitis” published in 2015. The reason for updating this chapter of the guideline were the current developments in the field of systemic therapy of atopic dermatitis.
T. Werfel+21 more
semanticscholar +1 more source
Background Atopic dermatitis is a chronic inflammatory skin disease associated with pruritus. Skin affected by atopic dermatitis not only shows a high percentage of Staphylococcus aureus colonization, but corneal barrier dysfunction is also known to ...
Shuhei Kubota+8 more
doaj +1 more source
Severe Atopic Dermatitis In Spain: A Real-Life Observational Study [PDF]
Objective: To determine the epidemiology and characterize the treatment prescribed for severe atopic dermatitis (AD) in children/adults in usual clinical practice.
Armario Hita, José Carlos+2 more
core +2 more sources
Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial. [PDF]
BACKGROUND: Skin barrier dysfunction precedes eczema development. We tested whether daily use of emollient in the first year could prevent eczema in high-risk children. METHODS: We did a multicentre, pragmatic, parallel-group, randomised controlled trial
BEEP study team+21 more
core +7 more sources
Retrospective Study: Atopic Dermatitis in Childhood
Background: Atopic dermatitis is a chronically and relapsing inflammatory skin disease affecting individuals with atopic history or their families. Atopic dermatitis affects all ageswith percentage 15-30% in children and 1-2% in adults. Chronic pruritus,
Kristina Sihaloho, Diah Mira Indramaya
doaj +1 more source
Consensus on the therapeutic management of atopic dermatitis - Brazilian Society of Dermatology [PDF]
: BACKGROUND: Atopic dermatitis is a highly prevalent inflammatory and pruritic dermatosis with a multifactorial etiology, which includes skin barrier defects, immune dysfunction, and microbiome alterations.
Valeria Aoki+17 more
doaj +1 more source
Atopic Dermatitis and Comorbidity [PDF]
Atopic dermatitis is the most common chronic inflammatory skin disease. It is often the first indicator of allergic diseases, and a certain percentage of patients are affected by allergic rhinitis and/or asthma as a consequence. The study aimed to investigate the link between atopic dermatitis and comorbidity in family medicine.
Sanja Bekić+5 more
openaire +3 more sources
Efficacy of combined peroxisome proliferator-activated receptor-α ligand and glucocorticoid therapy in a murine model of atopic dermatitis. [PDF]
Although topical glucocorticoids (GCs) show potent anti-inflammatory activity in inflamed skin, they can also exert numerous harmful effects on epidermal structure and function.
Crumrine, Debra+5 more
core +1 more source