Results 71 to 80 of about 300,331 (272)
Clinical Pharmacology in Drug Development, EarlyView.Abstract Clascoterone is an androgen receptor inhibitor approved for the treatment of acne vulgaris in patients 12 years of age and older. Here, we report results of 5 phase 1 studies that assessed the pharmacokinetics (PK), safety, and skin irritation and sensitization potential of clascoterone cream 1% in healthy participants and patients with acne ...
Andrea Francesco Daniele Di Stefano +8 more
wiley +1 more source
Monitoring of atopic dermatitis using leaky coaxial cable [PDF]
, 2017 In our daily life, inadvertent scratching may increase the severity of skin diseases (such as atopic dermatitis, etc.). However, people rarely pay attention to this matter, so the known measurement behavior of the movement is also very little ...
Abbasi, Qammer Hussain +9 more
core +1 more source
Oxidative Stress and Atopic Dermatitis
Antioxidants, 2020 Atopic dermatitis is a common chronic/chronically relapsing inflammatory skin disease, with increasing worldwide prevalence. Etiopathogenesis is complex and multifactorial, with a mix of genetic, immunological and environmental aspects.
L. Bertino +5 more
semanticscholar +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Novel compounds targeting the adaptive immune system are commonly initially investigated in healthy volunteers (HV). HV frequently lack constitutively expressed drug‐target engagement biomarkers, complicating the evaluation of pharmacological activity. The keyhole limpet hemocyanin (KLH) neo‐antigen challenge elicits a controlled immune response in HV ...
Micha N. Ronner +10 more
wiley +1 more source
, 2007 A distressed mother attends the clinic with her three year old daughter, who developed an itchy rash. The rash is reddish and affects her face and wrists. The child is restless and has been scratching all night.
Formosa, Marie Claire
core
Sex hormones in allergic conjunctivitis: altered levels of circulating androgens and estrogens in children and adolescents with vernal keratoconjunctivitis [PDF]
, 2015 PURPOSE: Vernal keratoconjunctivitis (VKC) is a chronic allergic disease mainly affecting boys in prepubertal age and usually recovering after puberty.
Bonini, S. +4 more
core +4 more sources
Counting the Burden: Atopic Dermatitis and Health-related Quality of Life
Acta Dermato-Venereologica, 2020 Atopic dermatitis is the most prevalent chronic inflammatory skin condition globally. The burden of atopic dermatitis on children and adults is extensive and there is also significant impact on the lives of patient caregivers and family members.
Faraz M. Ali, J. Vyas, A. Finlay
semanticscholar +1 more source
Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model
Barrier Immunity, EarlyView.ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia +4 more
wiley +1 more source
Early probiotic supplementation for the prevention of atopic disease in newborns-probiotics and the hygiene hypothesis-. [PDF]
, 2011 Environmental factors during early infancy could theoretically affect immune system development and subsequent risk of allergic disease. One potentially helpful exposure is early infant supplementation with specific probiotic strains.
Cabana, Michael D
core +3 more sources
Eye &ENT Research, EarlyView.Abstract IgG4‐related chronic rhinosinusitis (IgG4‐related CRS) is gaining recognition among various specialized physicians. As a systemic disease involving multiple organs, IgG4‐related CRS is still not widely recognized as an independent clinical entity. Given the complexity of diagnosing autoimmune‐related multisystem diseases, early recognition and
Lianqi Wan +3 more
wiley +1 more source