Results 81 to 90 of about 300,331 (272)

FADS Gene Cluster Polymorphisms: Important Modulators of Fatty Acid Levels and Their Impact on Atopic Diseases [PDF]

, 2009
Long-chain polyunsaturated fatty acids (LC-PUFAs) play an important role in several physiological processes and their concentration in phospholipids has been associated with several complex diseases, such as atopic disease.
Heinrich, Joachim, Illig, Thomas, Koletzko, Berthold, Lattka, Eva   +3 more
core   +1 more source

The Impact of Lactobacillus paracasei subsp. Paracasei on Oxytetracycline‐Induced Anxiety‐Like Behavior of Zebrafish via Regulation of Gut Microbiota and Brain Fatty Acid Metabolism

Food Frontiers, EarlyView.
LPSP exhibited considerable potential in reversing OTC‐induced anxiety‐like behavior. Combined with gut microbiomics and metabolomics, we revealed the underlying mechanisms. ABSTRACT The use of oxytetracycline (OTC) in aquaculture is crucial for fish health and disease prevention, but it might accumulate in humans through the food chain, potentially ...
Yang Qiu, Jiaxin Guo, Jie Zhang, Chenxu Xue, Wanjun He, Zhenquan Huo, Jiajin Zhu   +6 more
wiley   +1 more source

Keratinocytes: innate immune cells in atopic dermatitis

Clinical and Experimental Immunology, 2020
The skin is a unique immune organ that constitutes a complex network of physical, chemical and microbiological barriers against external insults. Keratinocytes are the most abundant cell type in the epidermis.
Panjit Chieosilapatham, Chanisa Kiatsurayanon, Y. Umehara, Juan Valentin Trujillo Paez, G. Peng, H. Yue, L. Nguyen, F. Niyonsaba   +7 more
semanticscholar   +1 more source

Influence of the sebaceous gland density on the stratum corneum lipidome [PDF]

, 2018
The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively.
Camera, Emanuela, Kozul, Nina, Ludovici, Matteo, Materazzi, Stefano, Picardo, Mauro, Risoluti, Roberta   +5 more
core   +1 more source

Systemic Immunomodulatory Treatments for Patients With Atopic Dermatitis

JAMA dermatology, 2020
Key Points Question What is the relative effectiveness of systemic treatments for patients with atopic dermatitis? Findings This network meta-analysis of 39 randomized clinical trials including 6360 patients found that dupilumab and cyclosporine were ...
A. Drucker, A. Ellis, M. Bohdanowicz, S. Mashayekhi, Zenas Z N Yiu, B. Rochwerg, Sonya Di Giorgio, B. Arents, T. Burton, P. Spuls, D. Küster, D. Siegels, J. Schmitt, C. Flohr   +13 more
semanticscholar   +1 more source

Impact of abnormal cesarean section scar formation on quality of life and postpartum depression: A cross‐sectional study in Japan

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To determine the prevalence of abnormal scar formation after cesarean section and evaluate its effects on quality of life (QoL) and postpartum depression risk. Methods A nationwide cross‐sectional study of 991 women aged 18–45 years at 6–18 months post‐cesarean section was conducted in Japan. Participants completed validated measures
Yosuke Sugita, Hiroaki Komatsu, Chisato Kodera, Daichi Urushiyama, Naosuke Enomoto, Sumito Nagasaki, Tamami Odai, Tokumasa Suemitsu, Yohei Onodera, Yoshihiko Hosokawa, Rei Ogawa   +10 more
wiley   +1 more source

Measurement properties of quality of life measurement instruments for infants, children and adolescents with eczema: protocol for a systematic review [PDF]

, 2016
Background: Eczema is a common chronic or chronically relapsing skin disease that has a substantial impact on quality of life (QoL). By means of a consensus-based process, the Harmonising Outcome Measures in Eczema (HOME) initiative has identified QoL as
AD Furlan, CB Terwee, CB Terwee, CB Terwee, CJ Apfelbacher, CJ Apfelbacher, CL Carroll, HC Williams, J Schmitt, J Schmitt, J Schmitt, J Schmitt, J Schmitt, JJ Grob, JM Schellingerhout, L Shamseer, LB Mokkink, LB Mokkink, LB Mokkink, LF Eichenfield, M Boers, PR Williamson, S Lewis-Jones, T Bieber   +23 more
core   +2 more sources

Genetic and Epigenetic Aspects of Atopic Dermatitis

International Journal of Molecular Sciences, 2020
Atopic dermatitis is a heterogeneous disease, in which the pathogenesis is associated with mutations in genes encoding epidermal structural proteins, barrier enzymes, and their inhibitors; the role of genes regulating innate and adaptive immune responses
B. Nedoszytko, E. Reszka, D. Gutowska-Owsiak, M. Trzeciak, M. Lange, J. Jarczak, M. Niedoszytko, E. Jabłońska, J. Romantowski, Dominik Strapagiel, J. Skokowski, Anna Siekierzycka, R. Nowicki, I. Dobrucki, A. Zaryczańska, L. Kalinowski   +15 more
semanticscholar   +1 more source

Mitochondrial dysfunction: Related diseases, influencing factors, and detection

Interdisciplinary Medicine, EarlyView.
Mitochondrial dysfunction is implicated in the pathogenesis of numerous diseases, including neurological disorders, cancers, and cardiovascular conditions, through mechanisms such as mitochondrial DNA mutations, dysregulation of mitochondrial network dynamics, and impaired mitophagy.
Zhaojin Li, Shiyu Li, Wanying Chen, Ziyu Zhang, Chun Pan, Peng Lei, Cheng Cheng, Junyou Zhu, Hanxiao Sun, Zhenning Dai   +9 more
wiley   +1 more source

Update on Atopic Dermatitis

Acta Médica Portuguesa, 2019
With an increasing prevalence during the past decades, atopic dermatitis has become a global health issue. A literature search following a targeted approach was undertaken to perform this non-systematic review, which intends to provide an overview of the epidemiology, pathophysiology, clinical features, comorbidities, and current therapies for the ...
Torres, Tiago, Ferreira, Eduarda Osório, Gonçalo, Margarida, Mendes-Bastos, Pedro, Selores, Manuela, Filipe, Paulo   +5 more
openaire   +6 more sources