Results 61 to 70 of about 518,303 (373)

PAM-HC: A Bayesian Nonparametric Construction of Hybrid Control for Randomized Clinical Trials Using External Data [PDF]

arXiv, 2023
It is highly desirable to borrow information from external data to augment a control arm in a randomized clinical trial, especially in settings where the sample size for the control arm is limited. However, a main challenge in borrowing information from external data is to accommodate potential heterogeneous subpopulations across the external and trial
arxiv  

Microbe-host interplay in atopic dermatitis and psoriasis

Nature Communications, 2019
Despite recent advances in understanding microbial diversity in skin homeostasis, the relevance of microbial dysbiosis in inflammatory disease is poorly understood.
N. Fyhrquist, Gareth Muirhead, S. Prast-Nielsen, M. Jeanmougin, P. Oláh, T. Skoog, Gerome Jules-Clement, Micha Feld, Mauricio Barrientos-Somarribas, H. Sinkko, E. H. van den Bogaard, P. Zeeuwen, G. Rikken, J. Schalkwijk, H. Niehues, W. Däubener, S. Eller, H. Alexander, D. Pennino, S. Suomela, Ioannis Tessas, E. Lybeck, A. Baran, H. Darban, R. S. Gangwar, U. Gerstel, Katharina Jahn, Piia Karisola, L. Yan, B. Hansmann, S. Katayama, S. Meller, M. Bylesjö, P. Hupé, F. Levi‐Schaffer, Dario Greco, A. Ranki, J. Schröder, J. Barker, J. Kere, S. Tsoka, A. Lauerma, V. Soumelis, F. Nestle, B. Homey, B. Andersson, H. Alenius   +46 more
semanticscholar   +1 more source

Halting Progression of Stasis Dermatitis: Community Perspectives and Strategies for Prevention [PDF]

, 2018
Complications of stasis dermatitis including venous ulcers, osteomyelitis, and cellulitis all significantly increase morbidity and mortality of disease.
Robbins, Allison B
core   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

THE INCIDENCE OF DERMATITIS IN FISHERMEN IN BONTANG CITY, EAST KALIMANTAN, INDONESIA

Public Health of Indonesia, 2019
Background: Occupational skin diseases are the most common occupational diseases in many countries. Dermatitis has become one of the top 10 occupational diseases (PAK) based on the potential incidence, severity, and prevention ability.
Dina Lusiana Setyowati, Risva Risva, Andi Anwar, Nurul Afiah   +3 more
doaj   +1 more source

Inference of Mixed Graphical Models for Dichotomous Phenotypes using Markov Random Field Model [PDF]

arXiv, 2022
In this article, we propose a new method named fused mixed graphical model (FMGM), which can infer network structures for dichotomous phenotypes. We assumed that the interplay of different omics markers is associated with disease status and proposed an FMGM-based method to detect the associated omics marker network difference. The statistical models of
arxiv  

Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis

JAMA dermatology, 2019
Key Points Question What is the efficacy and safety of dupilumab monotherapy in adolescents with moderate to severe inadequately controlled atopic dermatitis?
E. Simpson, A. Paller, E. Siegfried, M. Boguniewicz, L. Sher, M. Gooderham, L. Beck, E. Guttman‐Yassky, D. Pariser, A. Blauvelt, J. Weisman, B. Lockshin, T. Hultsch, Qin Zhang, M. Kamal, John D. Davis, B. Akinlade, H. Staudinger, J. Hamilton, N. Graham, G. Pirozzi, A. Gadkari, L. Eckert, N. Stahl, G. Yancopoulos, M. Ruddy, A. Bansal   +26 more
semanticscholar   +1 more source

Efficacy of combined peroxisome proliferator-activated receptor-α ligand and glucocorticoid therapy in a murine model of atopic dermatitis. [PDF]

, 2011
Although topical glucocorticoids (GCs) show potent anti-inflammatory activity in inflamed skin, they can also exert numerous harmful effects on epidermal structure and function.
Crumrine, Debra, Elias, Peter M, Feingold, Kenneth R, Fujiwara, Sakuhei, Hatano, Yutaka, Katagiri, Kazumoto   +5 more
core   +1 more source

Dosimetric effect of silicone‐based gel on skin surface during volumetric modulated arc therapy for breast cancer

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aims to quantify and compare the dosimetric effects of varying thicknesses of StrataXRT, a silicone‐based gel, and other topical agents on the skin surface during volumetric modulated arc therapy (VMAT) for breast cancer.
Tenyoh Suzuki, Shingo Ohira, Mami Ogita, Takeshi Ohta, Yuki Nozawa, Masanari Minamitani, Takuya Hayashi, Shigeki Saegusa, Toshikazu Imae, Tsuyoshi Ueyama, Atsuto Katano, Hideomi Yamashita, Weishan Chang, Keiichi Nakagawa   +13 more
wiley   +1 more source

Comparative Analysis of Drug-GPT and ChatGPT LLMs for Healthcare Insights: Evaluating Accuracy and Relevance in Patient and HCP Contexts [PDF]

arXiv, 2023
This study presents a comparative analysis of three Generative Pre-trained Transformer (GPT) solutions in a question and answer (Q&A) setting: Drug-GPT 3, Drug-GPT 4, and ChatGPT, in the context of healthcare applications. The objective is to determine which model delivers the most accurate and relevant information in response to prompts related to ...
arxiv