Results 41 to 50 of about 3,318,202 (320)
Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin
Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis+6 more
wiley +1 more source
Background: Adverse drug reactions increase morbidity and mortality, and potential drug interactions (DIs) increase the probability of adverse drug reactions.
Ying-Jui Chang+6 more
doaj +1 more source
Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani+4 more
wiley +1 more source
Injection site reactions with the use of biological agents
Injection site reactions (ISRs) are a local phenomenon defined as a constellation of symptoms, including swelling, erythema, pruritus, and pain around the site of injection. This article reviews the different aspects of ISRs, including their epidemiology
E. Thomaidou, Y. Ramot
semanticscholar +1 more source
Human Skin Models in Biophotonics: Materials, Methods, and Applications
This review discusses how the optical properties of human skin can be replicated in human skin models. It describes the principles, materials, and techniques used to develop artificial skin for biophotonics research. Finally, the article highlights recent advances and shows how these models improve the study of light‐skin interactions without the need ...
Dardan Bajrami+4 more
wiley +1 more source
Biologics in dermatology: An integrated review
The advent of biologics in dermatologic treatment armentarium has added refreshing dimensions, for it is a major breakthrough. Several agents are now available for use.
Virendra N Sehgal+2 more
doaj +1 more source
Efficacy and safety of dupilumab in two adolescents with severe atopic dermatitis
We report the cases of two adolescent siblings with severe atopic dermatitis, who, despite weighing approximately 40kg, presented a good response to dupilumab with the off-label dose for individuals aged 12 years and weighing 60kg.
Mara Giavina-Bianchi+1 more
doaj +2 more sources
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang+3 more
wiley +1 more source
Oral Lesions in Common Dermatologic Disorders: A Review Article
Skin as the largest organ, is influenced by wide variety of environmental and external factors. In addition many internal diseases can involve skin. Oral cavity and skin have close contact with each other Like skin which has contact with various external
Negar Sajjadian, Rahmatolah Salmanpoor
doaj
This study investigates how the mode of application affects drug delivery from coated microneedles. Combining finite element modeling with custom 3D‐printed Franz Diffusion Cells, the researchers found that prolonged application pressure from microneedles in situ reduces drug permeation.
Wenting Shu+5 more
wiley +1 more source