Results 61 to 70 of about 1,524,954 (299)

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Modulation of mu-opioid pathway for the treatment of pruritus: a systematic review of 1,146 patients

Journal of Dermatological Treatment
Background Pruritus is a debilitating symptom and conventional therapies often provide incomplete relief. The μ-opioid receptor (MOR) pathway is a key regulator of itch, and μ-pathway–modulating agents are increasingly used off-label for refractory ...
Khalid M. A. Ahmed, Amro Abu Suleiman, Alaa I. Alnajdawi, Dina Abdulkader, Ahmed M. Ahmed, Ahmed R. A. Moustafa, Emma Horton   +6 more
doaj   +1 more source

Paclitaxel-related dermatological problems: Not only alopecia occurs

Taiwanese Journal of Obstetrics & Gynecology, 2019
Objective: Dermatological problems after chemotherapy are often neglected with gynecological oncologists. Since paclitaxel is one of most popular agents for gynecology organ-related cancers, dermatologic change after paclitaxel treatment is seldom ...
Ming-Hsuan Su, Guan-Yeu Chen, Jun-Hung Lin, Howard Hao Lee, Kai-Cheng Chung, Peng-Hui Wang   +5 more
doaj   +1 more source

Dermatologic Consultations in the Hospital Setting

, 1994
BACKGROUND AND DESIGN: Dermatologic practice occurs mainly in the outpatient setting. The reasons for, frequency, and impact of inpatient dermatologic consultation are largely unstudied.
Rae, Virginia, Ceballos, Patricia I, Schachner, Lawrence A, Liang, Grace, Banks, Ray, Gonzalez, Ana, Falanga, Vincent   +6 more
core   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Potential drug interactions in dermatologic outpatient prescriptions—experience from nationwide population-based study in Taiwan

Dermatologica Sinica, 2011
Background: Adverse drug reactions increase morbidity and mortality, and potential drug interactions (DIs) increase the probability of adverse drug reactions.
Ying-Jui Chang, Min-Li Yeh, Yu-Chuan Li, Chien-Yeh Hsu, Yung-Tai Yen, Po-Yen Wang, Thomas Waitao Chu   +6 more
doaj   +1 more source

Pruritus to anticancer agents targeting the EGFR, BRAF, and CTLA-4

, 2013
In the past decade, the expanded use of targeted anticancer drugs has significantly prolonged survival in patients treated for a variety of cancers. Despite their increased specificity, agents such as epidermal growth factor receptor inhibitors (EGFRIs),
Fischer, Alyssa, Lacouture, Mario E., Ensslin, Courtney J., Wu, Shenhong, Rosen, Alyx C.   +4 more
core   +1 more source

Perioperative Management of Anticoagulation and Antiplatelet Therapy for Cutaneous Surgery: Different Approaches Among Dermatologic & Plastic and Reconstructive Surgeons

, 2021
Background: Despite increasing cross-collaboration between providers who perform cutaneous surgery, a disparity still exists in the current practices regarding perioperative management.
Han, J (via Mendeley Data)
core   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source

Strategies to reduce the risk of surgical site infections of the skinCapsule Summary

JAAD Reviews
Surgical site infection represents the most common complication in dermatologic surgery and with an estimated incidence ranging from 0.5% to 3%. The majority of surgical site infection can be prevented by implementing evidence-based strategies supported ...
Jalal Maghfour, MD, Shang I. Brian Jiang, MD   +1 more
doaj   +1 more source