Results 91 to 100 of about 484,964 (356)

METTL3/ALKBH5‐Mediated N6‐Methyladenosine Modification Drives Macrophage M1 Polarization via the SLC15A3‐TASL‐IRF5 Signaling Axis in Psoriasis

Advanced Science, EarlyView.
m6A modification stabilizes Slc15a3 mRNA in macrophages, activating the SLC15A3‐TASL‐IRF5 axis and promoting psoriatic inflammation. Abstract Impaired N6‐methyladenosine (m6A) modification has been implicated in regulating various inflammatory diseases, but its role in psoriasis remains unclear.
Tao Huang, Shijun Chen, Ke Ding, Liyan Yuan, Weiqi Lv, Kechen Chen, Yuchen Liu, Dongzhao Ma, Xin Zhang, Xiaobo Wang, Guanzheng Luo, Bin Yang, Ying Lin, Zhili Rong   +13 more
wiley   +1 more source

A Case of Palmoplantar Keratodermas Complicated by Pseudoainhum and Literature Review

Clinical, Cosmetic and Investigational Dermatology
Junhong Ye,1 Wen Li,1 Xianxu Yang,1 Yanhai Shi,2 Wen Lv3 1Department of Plastic Surgery and Skin Disease, Hainan Fifth People’s Hospital, Haikou City, Hainan Province, People’s Republic of China; 2Department of Skin Disease, Qionghai People’s Hospital ...
Ye J, Li W, Yang X, Shi Y, Lv W
doaj  

The scientometric characteristics of lichen planus in stomatology and dermatology journals: A comparative study

Journal of Dental Sciences
Background/purpose: Lichen planus (LP) is a representative mucocutaneous disease involving oral mucosa and skin. The aim of this study was to compare the scientometric characteristics of LP publications in stomatology and dermatology journals.
Qingqing Liu, Yiwen Deng, Wei Liu, Zhengyu Shen   +3 more
doaj   +1 more source

Research in Cosmetic Dermatology: Reconciling medicine with business [PDF]

Cosmetic dermatology is a marriage between medicine and business. Research in cosmetic dermatology shares the fundamental principles of clinical and pharmaceutical research.
Eapen, Bell R
core   +1 more source

The molecular genetic analysis of the expanding pachyonychia congenita case collection [PDF]

, 2014
BACKGROUND: Pachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma and nail dystrophy, often accompanied by oral leucokeratosis, cysts and follicular keratosis.
Al-Asadi, E., Hansen, C. D., McLean, W. H. I., Milstone, L. M., O'Toole, E., Schwartz, M. E., Shepherd, A. A., Smith, F. J. D., Sprecher, E., Wilson, N. J.   +9 more
core   +2 more sources

Harnessing the Immunomodulation of UV‐Exposed Keratinocyte Extracellular Vesicles for Inflammatory Disorder Treatment

Advanced Science, EarlyView.
Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu, Ding Yang, Jingsen Ji, Gengyou Li, Haoting Chen, Yuying Yao, Chenxing Fu, Fangling Liao, Jinzhao Liu, Yaming Zhang, Zechuan Li, Jing Zhang, Huike Ma, Jingxia Zhao, Ying‐Shi Sun, Weisheng Guo, Weiping Wang   +16 more
wiley   +1 more source

Investigating the Impact of Circulating Immune Cells on Acne Using Mendelian Randomization

Clinical, Cosmetic and Investigational Dermatology
Xudong Wang,1,2,* Shaoyu Guan,3,* Zhikuan Xia,2 Xin Zhang,2 Yu Bai,2 Qiang Li,4 Haitao Li,2 Rongya Yang2 1Southern Medical District of Chinese PLA General Hospital, Beijing, 100843, People’s Republic of China; 2Department of Dermatology ...
Wang X, Guan S, Xia Z, Zhang X, Bai Y, Li Q, Li H, Yang R   +7 more
doaj  

Long-term safety and efficacy of trifarotene 50 μg/g cream, a first-in-class RAR-γ selective topical retinoid, in patients with moderate facial and truncal acne. [PDF]

, 2020
BackgroundTreatment for both facial and truncal acne has not sufficiently been studied.ObjectivesTo evaluate the long-term safety and efficacy of trifarotene in both facial and truncal acne.MethodsIn a multicentre, open-label, 52-week study, patients ...
Ahmad, F, Alió Saenz, A, Blume-Peytavi, U, Cook-Bolden, F, Dirschka, T, Draelos, Z, Eichenfield, L, Fowler, J, Graeber, M, Kemény, L, Rich, P, Tanghetti, E   +11 more
core  

Keratitis-ichthyosis-deafness syndrome, atypical connexin GJB2 genemutation, and peripheral T-cell lymphoma: more than a random association? [PDF]

, 2011
Keratitis-ichthyosis-deafness (KID) syndrome is a rare congenital disorder characterized by a variety of skin lesions— that is, palmoplantar keratoderma, thickening of the skin, and erythematous verrucous lesions—neurosensorial hypoacusia, and keratitis
Contini, Salvatore, Cottoni, Francesca Maria Giovanna, Cucca, Francesco, Fozza, Claudio, Galleu, Antonio, Longinotti, Maurizio Roberto, Poddie, Fausto Pier'Angelo   +6 more
core   +3 more sources

Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C

Advanced Science, EarlyView.
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li, Xinzhu Li, Xiao Xiang, Jundong Huang, Xinyu Shen, Mengyue Wang, Jingwei Jiang, Shiwen Shao, Zeming Li, Tian Xie, Deming Liu, Yiping Zhao, Rui Ma, Wenyu Wu, Wei Shi, Cheng‐Ming Chuong, Ji Li, Mingxing Lei   +17 more
wiley   +1 more source