Results 121 to 130 of about 639,141 (400)

PSYCHOSOCIAL ISSUES IN DERMATOLOGY

open access: yesEuropean Medical Journal Dermatology, 2017
Skin, with its many biological functions, has a unique aesthetic value and determines the self-image and psyche of the person in terms of how they think about themselves. In modern times, smooth-textured flawless skin is a preferred characteristic.
Mukku Shiva Shanker Reddy   +1 more
doaj  

Harnessing autophagy to overcome mitogen‐activated protein kinase kinase inhibitor‐induced resistance in metastatic melanoma [PDF]

open access: yes, 2019
Background Patients with malignant melanoma often relapse after treatment with BRAF and/or mitogen‐activated protein kinase kinase (MEK) inhibitors (MEKi) owing to development of drug resistance.
Alexander, M.   +6 more
core   +1 more source

Cinobufagin Directly Targets PDE4D to Disrupt Fibroblast–Dendritic Cell Crosstalk in Atopic Dermatitis

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing revealed that MIF signaling drives inflammatory fibroblastmyeloid cell crosstalk in atopic dermatitis. Cinobufagin, a potent PDE4D inhibitor, suppresses MIF and reduces inflammation by restoring the cAMP/PKA/CREB pathway. Genetic knockout validates PDE4D as a key driver and promising therapeutic target for atopic dermatitis ...
Shicong Li   +14 more
wiley   +1 more source

Recurrent Subcutaneous Abscess from Co-Infection with Prototheca wickerhamii and Mycobacterium haemophilum: mNGS Misdiagnosis as Leprosy

open access: yesInfection and Drug Resistance
Li Jiang,1– 3,* Lili Wei,1– 3,* Xiuying Li,1– 3 Dongyan Zheng,1– 3 Cunwei Cao,1– 3 Meng Li2,4 1Department of Dermatology and Venereology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, People’s Republic of ...
Jiang L   +5 more
doaj  

Efficacy of Super-Bioavailable Itraconazole and Conventional Itraconazole at Different Dosing Regimens in Glabrous Tinea Infection - A Randomized Clinical Trial [Corrigendum]

open access: yesDrug Design, Development and Therapy, 2023
Shenoy MM, De A, Shah B, et al. Drug Des Devel Ther. 2023;17:2899-2908. The authors have advised the affiliation indicators in the author list on page 2899 is incorrect. The correct author list and affiliations are as follows.
Shenoy MM   +18 more
doaj  

Bimatoprost in dermatology

open access: yesIndian Dermatology Online Journal, 2018
Bimatoprost is a prostamide analogue used for treatment of glaucoma in ophthalmology. Surprisingly, the side effects such as increased pigmentation of eyelids and hypertrichosis in patients being treated with prostaglandin analogues for glaucoma have opened new areas of application in various dermatological disorders such as alopecia mainly affecting ...
Rashmi Sarkar   +5 more
openaire   +4 more sources

The use of drug calendars for the diagnosis of cutaneous drug eruptions in the age of electronic medical records [PDF]

open access: yes, 2020
A morbilliform drug eruption is the most common condition leading to a dermatology consultation for a patient in the hospital. Timing is an important diagnostic tool since the onset of a skin rash usually takes place within days-to-weeks of the start of ...
Cohen, Philip R, Grossman, Marc E
core  

Real-life effectiveness of once-daily calcipotriol and betamethasone dipropionate gel vs. ointment formulations in psoriasis vulgaris: final analysis of the 52-week PRO-long study [PDF]

open access: yes, 2015
Background: Topical therapies are the mainstay of treatment for psoriasis vulgaris. The fixed combination of calcipotriol (Cal) 50 mu g/g plus betamethasone 0.5 mg/g (as dipropionate; BD) is a first-line topical treatment and available as a gel or ...
Hol, CW, Lambert, Jo, Vink, J
core   +1 more source

Arginine Metabolic Disruption Impairs Hair Regeneration via ROS‐Mediated Inactivation of mTOR Signaling in Androgenetic Alopecia

open access: yesAdvanced Science, EarlyView.
Arginine deficiency accelerates androgenetic alopecia. Serum metabolome shows reduced circulating arginine, while local metabolic disruption depletes follicular reserves, triggering reactive oxygen species (ROS) accumulation and mTOR suppression that induce hair miniaturization.
Shixin Duan   +19 more
wiley   +1 more source

A Case of Palmoplantar Keratodermas Complicated by Pseudoainhum and Literature Review

open access: yesClinical, Cosmetic and Investigational Dermatology
Junhong Ye,1 Wen Li,1 Xianxu Yang,1 Yanhai Shi,2 Wen Lv3 1Department of Plastic Surgery and Skin Disease, Hainan Fifth People’s Hospital, Haikou City, Hainan Province, People’s Republic of China; 2Department of Skin Disease, Qionghai People’s Hospital ...
Ye J, Li W, Yang X, Shi Y, Lv W
doaj  

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