Results 11 to 20 of about 49,613 (221)

SCLC, Paraneoplastic Dermatomyositis, Positive Transcription Intermediary Factor 1-γ, and Point Mutation in the Transcription Intermediary Factor 1-γ Coding Gene: A Case Report

JTO Clinical and Research Reports, 2021
SCLC is frequently associated with paraneoplastic syndromes, including dermatomyositis. Patients with malignancy-associated dermatomyositis express a specific autoantibody pattern usually positive for anti–transcription intermediary factor 1-γ (TIF1-γ ...
Johnathan Arnon, MD, Anna Elia, MD, Yuval Nevo, PhD, Alexander Lossos, MD, Hovav Nechushtan, MD, PhD   +4 more
doaj   +1 more source

Multicenter Prospective Study of the Efficacy and Safety of Combined Immunosuppressive Therapy With High‐Dose Glucocorticoid, Tacrolimus, and Cyclophosphamide in Interstitial Lung Diseases Accompanied by Anti–Melanoma Differentiation–Associated Gene 5–Positive Dermatomyositis

Arthritis & Rheumatology, 2020
Interstitial lung disease (ILD) accompanied by anti–melanoma differentiation–associated gene 5 (anti–MDA‐5)–positive dermatomyositis (DM) is often rapidly progressive and associated with poor prognosis.
H. Tsuji, R. Nakashima, Y. Hosono, Y. Imura, M. Yagita, H. Yoshifuji, S. Hirata, T. Nojima, E. Sugiyama, K. Hatta, Y. Taguchi, M. Katayama, K. Tanizawa, T. Handa, R. Uozumi, S. Akizuki, K. Murakami, M. Hashimoto, Masao Tanaka, K. Ohmura, T. Mimori   +20 more
semanticscholar   +1 more source

Association between a C8orf13-BLK polymorphism and polymyositis/dermatomyositis in the Japanese population: an additive effect with STAT4 on disease susceptibility. [PDF]

PLoS ONE, 2014
BACKGROUND:Accumulating evidence has shown that several non-HLA genes are involved in the susceptibility to polymyositis/dermatomyositis. This study aimed to investigate the involvement of C8orf13-BLK, one of the strongest candidate genes for autoimmune ...
Tomoko Sugiura, Yasushi Kawaguchi, Kanako Goto, Yukiko Hayashi, Takahisa Gono, Takefumi Furuya, Ichizo Nishino, Hisashi Yamanaka   +7 more
doaj   +1 more source

Prevalence and reactivity of anti-melanoma differentiation-associated gene 5 (anti-MDA-5) autoantibody in Brazilian patients with dermatomyositis [PDF]

Anais Brasileiros de Dermatologia, 2018
: Background: There have been no studies to date on the frequency and reactivity of aanti-melanoma differentiation-associated gene 5 (anti-MDA-5) in samples from the Brazilian population with dermatomyositis. Objectives: To analyze this autoantibody in
Isabela Bruna Pires Borges, Marilda Guimarães Silva, Samuel Katsuyuki Shinjo   +2 more
doaj   +1 more source

Anti-PL-7 antibody-positive dermatomyositis with progressive interstitial pneumonia complicated with tracheal ulcer

Respiratory Medicine Case Reports, 2021
Tracheobronchial lesions are rare extramuscular complications for idiopathic inflammatory myopathies including dermatomyositis. We herein report a 65-year-old woman with tracheal ulcer during the progression of dermatomyositis-associated interstitial ...
Shintaro Sato, Hideaki Yamakawa, Tamiko Takemura, Tomohiko Nakamura, Tomohiro Oba, Tomotaka Nishizawa, Rie Kawabe, Keiichi Akasaka, Masako Amano, Hidekazu Matsushima   +9 more
doaj   +1 more source

Different phenotypes in dermatomyositis associated with anti-MDA5 antibody: Study of 121 cases.

Neurology, 2020
OBJECTIVES The predominance of extramuscular manifestations (e.g., skin rash, arthralgia, interstitial lung disease [ILD]) as well as the low frequency of muscle signs in anti-melanoma differentiation-associated gene 5 antibody-positive (anti-MDA5 ...
Y. Allenbach, Y. Uzunhan, S. Toquet, G. Leroux, L. Gallay, Alicia Marquet, A. Meyer, C. Guillaud, N. Limal, F. Gagnadoux, B. Hervier, R. Borie, C. Deligny, B. Terrier, A. Bérézné, S. Audia, N. Champtiaux, H. Devilliers, N. Voermans, E. Diot, A. Servettaz, T. Marhadour, V. Castelain, S. Humbert, C. Blanchard-Delaunay, N. Tieulié, P. Charles, M. Gérin, A. Mékinian, P. Priou, J. Meurice, A. Tazi, V. Cottin, M. Miyara, B. Grange, D. Israëł-Biet, S. Phin-Huynh, C. Bron, L. de Saint Martin, N. Fabien, K. Mariampillai, H. Nunes, O. Benveniste   +42 more
semanticscholar   +1 more source

Development and validation of a nomogram risk prediction model for malignancy in dermatomyositis patients: a retrospective study [PDF]

PeerJ, 2021
Background Dermatomyositis accompanied with malignancy is a common poor prognostic factor of dermatomyositis. Thus, the early prediction of the risk of malignancy in patients with dermatomyositis can significantly improve the prognosis of patients ...
Jiaojiao Zhong, Yunan He, Jianchi Ma, Siyao Lu, Yushi Wu, Junmin Zhang   +5 more
doaj   +2 more sources

Dermatomyositis

Neurology, 2021
Background and Objectives Discoveries of dermatomyositis-specific antibodies (DMSAs) in patients with dermatomyositis raised awareness of various myopathologic features among antibody subtypes.
J. Tanboon, M. Inoue, Yoshihiko Saito, Hisateru Tachimori, S. Hayashi, Satoru Noguchi, N. Okiyama, Manabu Fujimoto, Ichizo Nishino   +8 more
semanticscholar   +1 more source

A case of dermatomyositis with anti-TIF1γ antibodies revealing isolated para-aortic lymphadenopathy metastatic recurrence of endometrial cancer: A case report

SAGE Open Medical Case Reports, 2020
Dermatomyositis is an inflammatory myopathy presenting with characteristic cutaneous eruption and may be accompanied by proximal muscle weakness. Dermatomyositis may represent a paraneoplastic syndrome in 15%–25% of cases and has rarely been associated ...
Darosa Lim, Océane Landon-Cardinal, Annie Belisle, Sandra Davar   +3 more
doaj   +1 more source

Study of Tofacitinib in Refractory Dermatomyositis: An Open‐Label Pilot Study of Ten Patients

Arthritis & Rheumatology, 2020
This open‐label 12‐week study was conducted to evaluate the efficacy and safety of tofacitinib, a JAK inhibitor, in treatment‐refractory active dermatomyositis (DM).
Julie J. Paik, L. Casciola-Rosen, Joseph Shin, J. Albayda, E. Tiniakou, D. Leung, L. Gutierrez-Alamillo, J. Perin, L. Florea, C. Antonescu, S. Leung, Grazyna Purwin, A. Koenig, L. Christopher‐Stine   +13 more
semanticscholar   +1 more source