Results 41 to 50 of about 35,808 (310)

An Update on Pemphigus Vulgaris in Pregnancy and Neonates: Management Options and Our Clinical-Laboratory Experience

Medicina
Background and Objectives: Pemphigus vulgaris (PV) is a rare autoimmune blistering disease caused by IgG au-toantibodies against desmoglein 1 and/or desmoglein 3, leading to flaccid blisters on the skin and mucous membranes.
Maksymilian Markwitz, Natalia Welc, Monika Bowszyc-Dmochowska, Magdalena Jałowska, Marian Dmochowski   +4 more
doaj   +1 more source

Direct and indirect immunofluorescence [PDF]

, 2010
A imunofluorescência é um valioso instrumento auxiliar no diagnóstico das dermatoses bolhosas autoimunes e desordens inflamatórias, uma vez que seus achados clínicos e histopatológicos podem não ser determinantes.
AOKI, Valéria, FREITAS, Elder L., FUKUMORI, Lígia M. I., OLIVEIRA, Zilda N. P., PÉRIGO, Alexandre M., SOUSA JR, Joaquim X.   +5 more
core   +2 more sources

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

Arthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Rituximab in the Management of Autoimmune Bullous Diseases: A Treatment-Resistant Case Series from a Single Central European Referral Center

Medicina
Background and Objectives: Rituximab (RTX) has been the predominant treatment for autoimmune bullous diseases (AIBDs). The objective of this research was to assess the advantages and safety characteristics of RTX treatment in individuals with AIBD.
Maciej Marek Spałek, Magdalena Jałowska, Monika Bowszyc-Dmochowska, Marian Dmochowski   +3 more
doaj   +1 more source

The need of dermatologists, psychiatrists and psychologists joint care in psychodermatology [PDF]

, 2017
The mind-skin connection has been studied since the nineteenth century. The last 40 years have set the development of new research areas which allowed the clarifying of how these two dimensions interact. The diseases that involve skin and mind constitute
Ader R, Arck PC, Azambuja R, Basavaraj KH, Bilbo SD, Botchkarev VA, Carmody J, Chen Y, Chopra D, Chopra D, Cohen S, Custance AC, Dalgard FJ, Damásio A, Dantzer R, Davidson RJ, Del Nero HS, Escalas J, Field T, Field T, Field TM, Fried RG, Garg A, Glaser R, Grossman P, Gupta MA, Gupta MA, Hall JM, Hanson R, Harth W, Hatfield RW, Hoffmann FS, Hussain D, Ironson G, Kabat-Zinn J, Kabat-Zinn J, Kiecolt-Glaser JK, Koo J, Lavda AC, Ludwig MWB, Marucha PT, McEwen BS, Mercan S, Montagu A, O'Sullivan RL, Pan W, Patterson CH, Paus R, Pert CB, Pert CB, Pert CB, Picardi A, Ramirez JM, Roberto Doglia Azambuja, Saleh HM, Segerstrom SC, Selye H, Shenefelt PD, Shenefelt PD, Silva MN, Slominski AT, Stahl JE, van Laarhoven AI   +62 more
core   +3 more sources

Dupilumab and Systemic Hematologic Malignancies: Case Series and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting 15%–20% of children and 3%–10% of adults. An increased risk of systemic lymphomas – but not leukemias – has been reported in patients with AD. Dupilumab, a monoclonal IgG4 antibody targeting IL‐4 and IL‐13 signaling, is approved for moderate‐to‐severe AD and is ...
Nello Tommasino, Cataldo Patruno, Francesca di Vico, Maddalena Napolitano   +3 more
wiley   +1 more source

Drug Hypersensitivity: A Correlation Study From Histopathology to Clinic

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Drug hypersensitivity (DH) can present with varied clinical and pathological manifestations that may mislead the referring physician. Available data regarding the concordance between pathological diagnosis and clinical findings in DH are scarce.
Olivier Philip, Morgane Stichelbout, Marie Verhasselt‐Crinquette, Baptiste Mille, Delphine Staumont‐Sallé, Frédéric Dezoteux   +5 more
wiley   +1 more source

Clinical Features of Paediatric Inflammatory Epidermolysis Bullosa Acquisita: A Case Series Study

Acta Dermato-Venereologica
Epidermolysis bullosa acquisita (EBA) rarely develops in childhood. This study retrospectively recruited paediatric patients with EBA (age ≤ 16 years), diagnosed by clinical and histopathological features and results of immunofluorescence, immunoblotting
Yuexin Zhang, Jingyang Dang, Ruoyu Li, Xixue Chen, Xuejun Zhu, Mingyue Wang   +5 more
doaj   +1 more source

Applicability of Novel Laser Scanning Microscopy Techniques in Demonstrating Characteristic Features of Porokeratosis: In Vivo and Ex Vivo Investigation

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Porokeratoses represent a group of keratinization disorders characterized histopathologically by the presence of a cornoid lamella. The recognition of porokeratosis as a genodermatosis, along with its association with increased risk of skin cancer, underscores the importance of accurate and timely diagnosis.
Rahime Inci, Noora Neittaanmäki, Jeemol James, Marica B. Ericson, Sirkku Peltonen, Despoina Kantere   +5 more
wiley   +1 more source

Histopathological Aspects of Common Immune Checkpoint Inhibitors Induced Skin Toxicities

JEADV Clinical Practice, EarlyView.
ABSTRACT Background The histological characteristics of checkpoint inhibitors‐related adverse events (cirAEs) are not well studied and there are conflicting data regarding their similarities and differences with their idiopathic counterparts. Objectives To investigate the histological characteristics of the most common cirAEs.
Christina Kemanetzi, Konstantinos Lallas, Elizabeth Lazaridou, Mattheos Bobos, Aikaterini Kyriakou, Myrto Trakatelli, George Lazaridis, Evangelos Karamitrousis, Dimitrios Dionysopoulos, Konstantia Loga, Aimilios Lallas, Stavroula Pervana, Zoe Apalla   +12 more
wiley   +1 more source