Results 1 to 10 of about 250,268 (351)

Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain

open access: yesScience Robotics, 2018
A multilayered e-dermis allows a prosthesis and an amputee to perceive a range of innocuous and noxious tactile stimuli. The human body is a template for many state-of-the-art prosthetic devices and sensors.
Luke E Osborn   +2 more
exaly   +2 more sources

Pre-vascularized dermis model for fast and functional anastomosis with host vasculature

open access: yesBiomaterials, 2019
Skin engineering for clinical applications has gained numerous advances, however, most of the available dermis substitutes are exogenous matrices acting for a limited time. Indeed, after implantation these matrices need to be colonized by host cells such
Claudia Mazio   +2 more
exaly   +2 more sources

Age-related evolutions of the dermis: Clinical signs, fibroblast and extracellular matrix dynamics

open access: yesMechanisms of Ageing and Development, 2019
Ageing is today a major societal concern that is intrinsically associated with the increase of life expectancy. Outside the context of severe degenerative diseases that affect the elderly populations, normal visible signs of ageing, notably skin sagging ...
Haydont Valerie   +2 more
exaly   +2 more sources

In vivo stiffness measurement of epidermis, dermis, and hypodermis using broadband Rayleigh-wave optical coherence elastography. [PDF]

open access: yesActa Biomaterialia, 2022
Traveling-wave optical coherence elastography (OCE) is a promising technique to measure the stiffness of biological tissues. While OCE has been applied to relatively homogeneous samples, tissues with significantly varying elasticity through depth pose a ...
Xu Feng   +4 more
semanticscholar   +1 more source

Aging in the dermis: Fibroblast senescence and its significance

open access: yesAging Cell, 2023
Skin aging is characterized by changes in its structural, cellular, and molecular components in both the epidermis and dermis. Dermal aging is distinguished by reduced dermal thickness, increased wrinkles, and a sagging appearance.
Jing Zhang   +3 more
semanticscholar   +1 more source

Assessing the Role of Carbonyl Adducts, Particularly Malondialdehyde Adducts, in the Development of Dermis Yellowing Occurring during Skin Photoaging

open access: yesLife, 2022
Solar elastosis is associated with a diffuse yellow hue of the skin. Photoaging is related to lipid peroxidation leading to the formation of carbonyl groups. Protein carbonylation can occur by addition of reactive aldehydes, such as malondialdehyde (MDA),
Hélène Zucchi   +5 more
doaj   +1 more source

Focus on the Contribution of Oxidative Stress in Skin Aging

open access: yesAntioxidants, 2022
Skin aging is one of the most evident signs of human aging. Modification of the skin during the life span is characterized by fine lines and wrinkling, loss of elasticity and volume, laxity, rough-textured appearance, and pallor.
Federica Papaccio   +3 more
doaj   +1 more source

Effect of Roflumilast Cream vs Vehicle Cream on Chronic Plaque Psoriasis: The DERMIS-1 and DERMIS-2 Randomized Clinical Trials.

open access: yesJournal of the American Medical Association (JAMA), 2022
Importance Once-daily roflumilast cream, 0.3%, a potent phosphodiesterase 4 inhibitor, demonstrated efficacy and was well tolerated in a phase 2b trial of patients with psoriasis.
M. Lebwohl   +25 more
semanticscholar   +1 more source

A mechanistic view on the aging human skin through ex vivo layer-by-layer analysis of mechanics and microstructure of facial and mammary dermis

open access: yesScientific Reports, 2022
Age-related changes in skin mechanics have a major impact on the aesthetic perception of skin. The link between skin microstructure and mechanics is crucial for therapeutic and cosmetic applications as it bridges the micro- and the macro-scale. While our
B. Lynch   +6 more
semanticscholar   +1 more source

Identification of Common Hub Genes in Human Dermal Fibroblasts Stimulated by Mechanical Stretch at Both the Early and Late Stages

open access: yesFrontiers in Surgery, 2022
BackgroundMechanical stretch is vital for soft tissue regeneration and development and is utilized by plastic surgeons for tissue expansion. Identifying the common hub genes in human dermal fibroblasts (HDFs) stimulated by mechanical stretch at different
Chen Dong   +8 more
doaj   +1 more source

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