Results 161 to 170 of about 1,746 (180)

Severe Thrombocytopenia and Dermonecrosis after Loxosceles Spider Bite in a 3-Year-Old Child

The Journal of Pediatrics, 2013
3-year-old girl was admitted for sudden onset of 12 hours of high fever, vomiting, malaise, and skin rash the day prior to admission, with no history of trauma or drugs. The patient showed a petechial and morbilliform rash, swelling, redness and a dry dark blue-purple lesion on the right big toe (Figure). Blood tests showed thrombocytopenia (18 10 9 /L)
Carina Levin, Dganit Rozemman, Waheeb Sakran, Raphaël Halevy, Sarit Peleg, Ariel Koren   +5 more
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Antibody-mediated protection against Staphylococcus aureus dermonecrosis and sepsis by a whole cell vaccine

Vaccine, 2017
Staphylococcus aureus is a very important human pathogen that causes significant morbidity and mortality worldwide. Several vaccine clinical trials based on generating antibody against staphylococcal surface polysaccharides or proteins have been unsuccessful.
Richard Malley
exaly   +3 more sources

Sphingomyelinases in the Venom of the SpiderLoxosceles intermediaAre Responsible for both Dermonecrosis and Complement-Dependent Hemolysis

Biochemical and Biophysical Research Communications, 1998
The bite of spiders of the genus Loxosceles can induce a variety of biological effects, including dermonecrosis and complement (C) dependent haemolysis. The aim of this study was to characterise the toxins in the venom responsible for the different biological effects.
Denise V Tambourgi
exaly   +3 more sources

High throughput drug discovery towards novel therapeutics for snakebite dermonecrosis

2023
Snakebite envenomation is a neglected tropical disease that kills over 100,000 people per year and injures more than 400,000. Brazil suffers more than 26,000 snakebites per year. It is estimated that 90% of all snakebite accidents in the Amazon region are caused by Bothrops species pit vipers.
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Loxosceles intermedia spider venom sphingomyelinases are responsible for both dermonecrosis and complement-dependent haemolysis

Toxicon, 2000

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[Enzootic dermonecrosis in chickens].

Veterinarno-meditsinski nauki, 1976
An enzootic of necrotic dermatosis in hen layers was described. The changes consisted in that they had constant localization and demarkated sites on the skin between the back and the neck. The disease was observed on a farm for 5000 layers in the course of two consecutive years.
R, Kasabov, S, Nachev
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Pattern of inflammatory response to Loxosceles intermedia venom in distinct mouse strains: A key element to understand skin lesions and dermonecrosis by poisoning

Toxicon, 2015
Envenomation caused by spiders Loxosceles induce intense dermonecrosis at the bite site and systemic disease. In this work we described the hyaluronidase and collagenase activities in vitro of the Loxosceles intermedia venom, but no phospholipase A2 activity. In vivo, we evaluated the effect of L. intermedia venom used different strain of mice, C57BL/6,
Marcos Monteiro-Machado
exaly   +3 more sources

Nanoemulsion containing Jatropha gossypiifolia leaf extract reduces dermonecrosis induced by Bothrops erythromelas venom and accelerates wound closure

Journal of Ethnopharmacology
The species Jatropha gossypiifolia, popularly known as "pinhão-roxo", is distributed throughout Brazil, is commonly employed for topical or oral administration in treating wounds, inflammations, and snake bites. Given the significant impact of snakebites on public health and the limitations of antivenom, coupled with the diverse molecular composition ...
Beatriz Ketlyn da Cunha Batista, João Felipe Oliveira da Silva, Júlia Gabriela Ramos Passos, Magda Rhayanny Assunção Ferreira, Luiz Alberto Lira Soares, Hugo Alexandre Oliveira Rocha, Arnóbio Antônio da Silva-Júnior, Jacinthia Beatriz Xavier-Santos, Matheus de Freitas Fernandes‐Pedrosa   +8 more
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A case report of conjunctivitis and dermonecrosis in rabbit due to Staphylococcus aureus.

The Indian veterinary journal, 1966
Bhambani Bd
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[Dermonecrosis along the course of the caudal branch of the lateral saphenous vein in foals due to a Staphylococcus aureus infection].

Tierarztliche Praxis, 1994
Necrosis of the skin on both lateral aspects of the hind limbs following the caudal branch of the lateral saphenous vein in 22 suckling foals is described. The first clinical signs were observed on days 2-5 post natum. S. aureus was isolated from the wounds.
K Elze, John Schulz, O. Rob
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