Results 201 to 210 of about 763,739 (333)

Extracellular vesicle proteomics identifies novel blood biomarkers for the early diagnosis of status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to identify novel blood‐based biomarkers associated with the early diagnosis of status epilepticus (SE) by exploring proteomic alterations in plasma extracellular vesicles (EVs). Methods We conducted an observational and prospective study in a two‐phase design: a discovery proteomic analysis of plasma EVs ...
Estevo Santamarina   +11 more
wiley   +1 more source

Interventions to promote child development in institutionalized children: a scoping review. [PDF]

open access: yesRev Esc Enferm USP
Martins V   +7 more
europepmc   +1 more source

Moderate increase of MET in hepatocytes protects against cholestatic liver injury by promoting an effective antioxidant response

open access: yesThe FEBS Journal, EarlyView.
Moderate overexpression of wild‐type Met in hepatocytes (Alb‐R26Met mouse model) boosts a strong antioxidant response dependent on the glutathione system while impairing TGF‐β signaling in the liver. This leads to improved liver regeneration and protects against DDC‐induced injury, a model for cholestatic disease sharing features with primary ...
Carlos González‐Corralejo   +16 more
wiley   +1 more source

Antagonistic regulation of nitrogen and drought signaling mediated by NIN-like protein 7 transcription factor in <i>Arabidopsis thaliana</i>. [PDF]

open access: yesProc Natl Acad Sci U S A
Johnson NR   +10 more
europepmc   +1 more source

Desarrollo de software de reconocimiento de matrículas de coche

open access: yes, 2014
En el presente trabajo final de carrera se pretende desarrollar un software, utilizando un sistema de visión artificial, que permita detectar automáticamente matrículas a partir de imágenes de coches y extraer el numero con un formato de texto legible por el ordenador. El trabajo se dividirá en dos etapas: • La primera etapa de adaptación con C++, y en
openaire   +2 more sources

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

open access: yesThe FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek   +12 more
wiley   +1 more source

Phytochemical Characterization and Antimicrobial Properties of a Hydroalcoholic Extract of Tristerix corymbosus (L) Kuijt, a Chilean Mistletoe Species Hosted on Salix babylonica (L). [PDF]

open access: yesAntibiotics (Basel)
Hidalgo AA   +10 more
europepmc   +1 more source

Elucidating the Molecular Basis in a Cohort of Patients With Combined Bleeding Tendencies and Joint Hypermobility Manifestations

open access: yesHaemophilia, EarlyView.
ABSTRACT Background In patients with unexplained bleeding and normal haemostatic parameters, heritable disorders of connective tissue (HDCT) may be an underlying cause due to vascular fragility, as observed in Ehlers–Danlos syndrome (EDS) or Marfan syndrome (MS). This study aims to investigate the molecular profile of patients with joint hypermobility (
Perla Bandini   +11 more
wiley   +1 more source

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