Investigated mutations in transthyretin (TTR) disrupt the F87‐centered hydrophobic core that stabilizes its tetrameric structure. The mild I107V mutation weakens inter‐chain packing, while H88R fully abolishes tetramer formation, yielding a monomeric, aggregation‐prone form. Structural, biophysical, and computational analyses reveal that both mutations
István L. Bódy +7 more
wiley +1 more source
Antagonistic regulation of nitrogen and drought signaling mediated by NIN-like protein 7 transcription factor in <i>Arabidopsis thaliana</i>. [PDF]
Johnson NR +10 more
europepmc +1 more source
What Job Would You Apply To? Findings on the Impact of Language on Job Searches
ABSTRACT This study examines whether gender‐inclusive language in job advertisements can increase women's interest in applying for male‐dominated occupations. We implemented a discrete choice experiment with 5679 participants in Argentina, Chile, Colombia, Mexico, and Peru. Each respondent evaluates multiple paired ads for the same job with job content
Ana Maria Diaz +3 more
wiley +1 more source
New Andes virus isolate haplotype obtained during prospective close contacts follow-up of an Hantavirus cardiopulmonary syndrome fatal case, Chile. [PDF]
Barrera A +11 more
europepmc +1 more source
Workflows flexibles para procesos de desarrollo de software
En el proceso de desarrollo software es preciso dirigir el trabajo de los agentes. Para orquestarlo, es necesario el uso de workflows, pero los procesos actuales no los ofrecen o son demasiado rígidos. TUNE-UP es una metodología y herramienta para proceso software que incluye un motor de workflows cuya principal característica es la flexibilidad.
openaire +2 more sources
Exploring drivers and costs of partial trans‐Saharan migration in juvenile vultures
Partial migration occurs when only a subset of individuals within a population undertakes a migratory journey. The decision to migrate can be influenced by intrinsic traits (e.g. sex or physical condition) as well as by extrinsic factors (e.g. social environment or resource availability).
Eneko Arrondo +18 more
wiley +1 more source
Optimizing cryopreservation protocols of Saccharomyces eubayanus using heat transfer modeling. [PDF]
Caruso MA +3 more
europepmc +1 more source
Novel TRIM Proteins Modulating the Innate Immune Response of Rainbow Trout (<i>Oncorhynchus mykiss</i>). [PDF]
Donoso F +9 more
europepmc +1 more source
Modelo para el desarrollo de arquitecturas de software
Las necesidades actuales que tiene toda organización para el logro de sus objetivos, demandan la contruscción de grandes y complejos sistemas de software, mismos que requieren de la combinación de diferentes tecnologías y ...
openaire +1 more source
Transcription-Coupled Repair Promotes the Retention of Mutations in Coding Regions During Replication Stress. [PDF]
Zambrano E +6 more
europepmc +1 more source

