Results 261 to 270 of about 518,963 (302)

Healthcare Provider Perspectives of Various Signs and Symptoms for Diagnosing Degenerative Cervical Myelopathy: Results of an International, Multidisciplinary Survey. [PDF]

Muscle Nerve
Burn LA, Rujeedawa T, Lalkhen A, Martin AR, MacDowall A, Kwon BK, Zipser CM, Treanor C, Anderson DB, Martin-Moore E, Guest J, Harrop JS, Milligan J, Furlan JC, Margetis K, Wood L, Onofrei LV, Vialle LR, Ito M, Kotter M, Fehlings MG, Lee MWY, Hutton M, Harel NY, Yurac R, Chauhan RV, Dugan S, Kalsi-Ryan S, Stacpoole S, Blizzard T, Boerger TF, Solberg TK, Lantz JM, Davies B, Tetreault L, AO Spine RECODE‐DCM Diagnostic Criteria Incubator.   +35 more
europepmc   +1 more source

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

Brain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña, Enric Vidal, Natalia Fernández‐Borges, Jorge M. Charco, Carlos M. Díaz‐Domínguez, Cristina Sampedro‐Torres‐Quevedo, Josu Galarza‐Ahumada, Eva Fernández‐Muñoz, Maitena San‐Juan‐Ansoleaga, Miguel Ángel Pérez‐Castro, Nuno Gonçalves‐Anjo, Patricia Piñeiro, Samanta Giler, Nora González‐Martín, Nuria L. Lorenzo, Africa Manero‐Azua, Guiomar Perez de Nanclares, Mariví Geijo, Manuel A. Sánchez‐Martín, Jesús R. Requena, Joaquín Castilla   +20 more
wiley   +1 more source

Region-Specific Expression Patterns of lncRNAs in the Central Nervous System: Cross-Species Comparison and Functional Insights. [PDF]

Int J Mol Sci
López-Royo T, Gascón E, Moreno-Martínez L, Macías-Redondo S, Zaragoza P, Manzano R, Osta R.   +6 more
europepmc   +1 more source

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

British Journal of Pharmacology, EarlyView.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert, Chantal Fitterer, Sylvain Hugel, Mila Jesic, Yannick Goumon, Virgine Andry, Severine Schneider, Francois Daubeuf, Abdelfattah Faouzi, Stephane Doridot, Susruta Majumdar, Frederic Bihel, Martine Schmitt, Dominique Massotte   +13 more
wiley   +1 more source

Fiber-specific differences in protein content of pathways related to mTORC1 signaling and oxidative metabolism in individuals with obesity. [PDF]

Sci Rep
Campos C, Flores-Opazo M, Valladares-Ide D, Cabello-Verrugio C, Parada P, Morales F, Arredondo J, Peñailillo L.   +7 more
europepmc   +1 more source

Addressing environmental misperceptions for nature recovery

Conservation Biology, EarlyView.
Abstract A poorly understood and systemic challenge to global conservation agreements is shifting baseline syndrome (SBS), wherein people misperceive the extent to which nature has changed. This can diminish societal expectations for nature recovery. We broadened the conceptual framing of SBS beyond the more common elements of nature loss to include ...
Shuo Gao, Sophus O. S. E. zu Ermgassen, Joseph W. Bull, E. J. Milner‐Gulland   +3 more
wiley   +1 more source

Differential cannabinergic effects on temporal perception and production. [PDF]

Neuropsychopharmacology
Martínez-Montalvo MG, Ortega-Romero DI, Báez-Cordero AS, Sánchez-Lobato O, Pérez-Díaz CI, Rueda-Orozco PE.   +5 more
europepmc   +1 more source

Parenting and stimulation for child development at home: perspectives from Nurturing Care. [PDF]

Rev Lat Am Enfermagem
Hilário JSM, Pancieri L, Lima RAG, Melo EMOP, Mello DF.   +4 more
europepmc   +1 more source

Examination of Motor Imagery Ability in Individuals With Diplegic Cerebral Palsy: Case-Control Study. [PDF]

Rev Neurol
Demirtas Karaoba D, Ozaltin GE, Candiri B, Talu B.   +3 more
europepmc   +1 more source

Overexpression of autophagy enhancer PACER/RUBCNL in neurons accelerates disease in the SOD1^G93A ALS mouse model. [PDF]

Biol Res
Labrador L, Rodriguez L, Beltran S, Hernandez F, Gomez L, Ojeda P, Bergmann C, Calegaro-Nassif M, Kerr B, Medinas DB, Manque P, Woehlbier U.   +11 more
europepmc   +1 more source