Results 41 to 50 of about 3,379 (196)

Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli, Karine Lacourse, Hélène Blais, Anne‐Sophie Deshaies‐Rugama, Cynthia Thompson, Alex Desautels, Jacques Montplaisir, Milan Nigam, Christophe Moderie, Boshra Khajehpiri, Catherine Duclos, Jean Marc Lina, Julie Carrier, Nadia Gosselin   +13 more
wiley   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source

Effect of training on the development of exercise-induced arterial hypoxemia in volleyball players

Physical Education of Students, 2020
Background and Study Aim. The purpose of this study was to examine the effect of volleyball training on the development of exercise-induced arterial hypoxemia during incremental exercise in male competitive volleyball players ...
Selcen Korkmaz Eryılmaz, Kerimhan Kaynak   +1 more
doaj   +1 more source

Longer and Deeper Desaturations Are Associated With the Worsening of Mild Sleep Apnea: The Sleep Heart Health Study

Frontiers in Neuroscience, 2021
Study ObjectivesObesity, older age, and male sex are recognized risk factors for sleep apnea. However, it is unclear whether the severity of hypoxic burden, an essential feature of sleep apnea, is associated with the risk of sleep apnea worsening.
Tuomas Karhu, Tuomas Karhu, Sami Myllymaa, Sami Myllymaa, Sami Nikkonen, Sami Nikkonen, Diego R. Mazzotti, Juha Töyräs, Juha Töyräs, Juha Töyräs, Timo Leppänen, Timo Leppänen   +11 more
doaj   +1 more source

Dual Aberrant Splicing Caused by an Apparently Missense CHD7 Variant, c.5273A>G (p.Asp1758Gly), in CHARGE Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT CHARGE syndrome is a rare congenital disorder primarily attributed to heterozygous pathogenic variants of the CHD7 gene. Most pathogenic CHD7 variants are loss‐of‐function (LoF) variants, whereas the interpretation of missense variants remains challenging in the absence of functional evidence for their pathogenicity.
Takashi Okuno, Tatsuto Shimizu, Aiko Igarashi, Kazumi Ikeda, Masamichi Ikawa, Sumihito Togi, Hiroki Ura, Yo Niida, Katsutsugu Umeda   +8 more
wiley   +1 more source

Results of CPAP Titration and Short-Term Adherence Rates in Patients with Obesity Hypoventilation Syndrome and Mild/Moderate Obstructive Sleep Apnea

Nature and Science of Sleep, 2022
Ahmed S BaHammam,1 Salih A Aleissi,1 Samar Z Nashwan,1 Awad H Olaish,1 Aljohara S Almeneessier1,2 1The University Sleep Disorders Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 2Department of Family and ...
BaHammam AS, Aleissi SA, Nashwan SZ, Olaish AH, Almeneessier AS   +4 more
doaj  

An Investigation of Sleep Macro‐ and Microarchitecture by APOE Genotype

Annals of Neurology, EarlyView.
Objectives Apolipoprotein E ε4 (APOE ε4), a robust genetic risk factor for Alzheimer's disease (AD) is associated with functional connectivity deficits and amyloid pathology in brain regions involved in sleep regulation. Thus, alterations in sleep architecture may be one pathway through which ε4 contributes to Alzheimer's disease vulnerability. However,
Gawon Cho, Anne Chen, Eunyoung Choi, Orfeu M. Buxton, Daniel Kay, Adam Mecca, Brienne Miner   +6 more
wiley   +1 more source

High-flow nasal cannula oxygenation reduces desaturation during percutaneous radiofrequency ablation under moderate sedation

Frontiers in Medicine
BackgroundThe majority of percutaneous radiofrequency ablation (PRFA) procedures for liver cancer are performed under ultrasound guidance and with moderate sedation.
Jiangling Wang, Jiangling Wang, Qicheng Wu, Qicheng Wu, Zewu Ding, Zewu Ding, Wen Zhang, Wen Zhang, Kangjie Xie, Xiaochun Mao, Xiangming Fang   +10 more
doaj   +1 more source

Static Metabolic Bubbles as Precursors of Vascular Gas Emboli During Divers’ Decompression: A Hypothesis Explaining Bubbling Variability

Frontiers in Physiology, 2019
IntroductionThe risk for decompression sickness (DCS) after hyperbaric exposures (such as SCUBA diving) has been linked to the presence and quantity of vascular gas emboli (VGE) after surfacing from the dive.
Jean-Pierre Imbert, Salih Murat Egi, Salih Murat Egi, Peter Germonpré, Peter Germonpré, Costantino Balestra, Costantino Balestra   +6 more
doaj   +1 more source

Fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in rat testicles

Journal of Lipid Research, 1973
A comparative study was made on the fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in various subcellular fractions of liver and testis from rats of different ages.
Sixta Ayala, Graciela Gaspar, Rodolfo R. Brenner, Raúl O. Peluffo, Wolf Kunau   +4 more
doaj   +1 more source