Results 121 to 130 of about 16,184 (258)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Highly ordered micro‐sphere films with finely tunable mono‐ to multi‐layer for optical anti‐counterfeiting

Droplet
Highly ordered films of polystyrene (PS) micro‐spheres have demonstrated various merits in optoelectronic devices, given their size‐ and thickness‐dependent optical properties.
Huanhuan Deng, Min Zhang, Xiaoxun Li, Xiao Wang, Ziqiu Fang, Lei Jiang, Huan Liu   +6 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Unified 1/2 scaling laws for droplet impact dynamics: From rigid to flexible thin films

Droplet
Droplet impact dynamics on solid surfaces, which are ubiquitously present in aerospace engineering, energy systems, agricultural production, etc., involve complex fluid–structure interactions.
Junming Peng, Xianfu Huang, Quanzi Yuan
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Unveiling nanodroplet impact force on material interfaces

Droplet
Nanodroplet impact on nanoscale material interfaces is widely involved in nanoscience and nanotechnology, affecting the technical reliability through complicated liquid‒solid interaction force, that is, the droplet impact force.
Zhifeng Hu, Haojiang Ran, Hanyi Liu, Bingqiang Ji, Jun Zhang, Fuqiang Chu   +5 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

New insights into suspended drops: When soft matter meets acoustic levitation

Droplet
Acoustic levitation has developed into a popular but elegant tool for the study of drops as well as soft matter due to its exceptional levitation capabilities to a variety of liquid samples.
Hongyue Chen, Zhenyu Hong, Duyang Zang
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Applying Inquiry-Based Learning (IBL) through Pictorial Riddle to Improve Students Ability to Write Descriptive Paragraph [PDF]

, 2013
The objective of this research was to find out whether or not the use of Inquiry-Based Learning (IBL) through Pictorial Riddle was able to improve students’ ability on content, organization, grammar, vocabulary, and mechanics of SMP Negeri 1 Suli.
Syam, Nurul Fajriah
core