Results 101 to 110 of about 5,615 (204)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Unveiling nanodroplet impact force on material interfaces

Droplet
Nanodroplet impact on nanoscale material interfaces is widely involved in nanoscience and nanotechnology, affecting the technical reliability through complicated liquid‒solid interaction force, that is, the droplet impact force.
Zhifeng Hu, Haojiang Ran, Hanyi Liu, Bingqiang Ji, Jun Zhang, Fuqiang Chu   +5 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

New insights into suspended drops: When soft matter meets acoustic levitation

Droplet
Acoustic levitation has developed into a popular but elegant tool for the study of drops as well as soft matter due to its exceptional levitation capabilities to a variety of liquid samples.
Hongyue Chen, Zhenyu Hong, Duyang Zang
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Liquid metal droplet dynamics

Droplet
The unique properties to combine the dual merits of both liquids and metals together make the gallium‐based liquid metal (LM) droplets a class of unconventional substitute which possess great potential for a group of newly emerging areas, such as ...
Xi Zhao, Mengwen Qiao, Yingxin Zhou, Jing Liu   +3 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Chemically robust superhydrophobic surfaces with a self‐replenishing nanoscale liquid coating

Droplet
Due to poor chemical robustness, superhydrophobic surfaces become susceptible to failure, especially in a highly oxidative environment. To ensure the long‐term efficacy of these surfaces, a more stable and environmentally friendly coating is required to ...
Xiaoteng Zhou, Pranav Sudersan, Diego Diaz, Benjamin Leibauer, Chirag Hinduja, Fahimeh Darvish, Pravash Bista, Lukas Hauer, Manfred Wagner, Werner Steffen, Jie Liu, Michael Kappl, Hans‐Jürgen Butt   +12 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source