Results 101 to 110 of about 16,184 (258)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
The Effect of Using Realia on the Seventh Grade Students’ Descriptive Paragraph Writing Achievement [PDF]
, 2020 Writing is claimed as one of the most complex skills to be mastered. Especially for the EFL students, like Indonesian students. It is because in producing a good writing, the students should consider five aspects.
QUDSIYAH, Dewi
core
DropletWhen microdroplets with quasi‐spherical contact angles coalesce together on a low‐adhesion substrate, the capillary‐inertial expansion of the liquid bridge induces a dramatic out‐of‐plane jumping event due to symmetry breaking. From the onset of merging,
Jonathan B. Boreyko
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Droplet collision of hypergolic propellants
DropletIn the present mini‐review, droplet impacting on a liquid pool, jet impingement, and binary droplet collision of nonreacting liquids are first summarized in terms of basic phenomena and the corresponding nondimensional parameters.
Chengming He, ZhiXia He, Peng Zhang
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Actuating droplets with electrowetting: Force and dynamics
DropletElectrowetting on dielectric (EWOD) allows rapid movement of liquid droplets on a smooth surface, with applications ranging from lab‐on‐chip devices to micro‐actuators. The in‐plane force on a droplet is a key indicator of EWOD performance.
Robert Hennig +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Knowledge and Application of Body Mechanics: Nurses of a Hospital in Ecuador
, 2021 Nursing is a profession that within its role should have knowledge and applicability of body mechanics in patient care, Ecuador maintains high statistics of musculoskeletal symptomatology related to the limited knowledge and applicability of body ...
Naranjo Chávez, Gladys Magdalena +2 more
core
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source