Results 41 to 50 of about 139,114 (288)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Understanding of the logic of nesting of the different realities of architectural space: pedagogical approach [PDF]

open access: yes, 2014
Ponencia presentada a Session 6: Los procesos de diseño como conocimiento / Design processes and ...
Bouricha Bouabid, Faïza   +1 more
core  

CONTRIBUTIONS FOR DEVELOPING OF A COMPUTER AIDED LEARNING ENVIRONMENT OF DESCRIPTIVE GEOMETRY

open access: yesJournal of Industrial Design and Engineering Graphics, 2009
The paper presents the authors’ contributions for developing a computer code for teaching of descriptive geometry using the computer aided learning techniques.
Antonescu Ion   +2 more
doaj  

General Explicit Solution of Planar Weakly Delayed Linear Discrete Systems and Pasting Its Solutions

open access: yesAbstract and Applied Analysis, 2014
Planar linear discrete systems with constant coefficients and delays x(k+1)=Ax(k)+∑l=1n‍Blxl(k-ml) are considered where k∈ℤ0∞:={0,1,…,∞}, m1,m2,…,mn are constant integer delays ...
Josef Diblík, Hana Halfarová
doaj   +1 more source

Shape Dependent EMA Model of Nanostructured Anisotropic Materials

open access: yesNanomaterials, 2019
Heterogeneous nanostructures containing nanoparticles of various sizes and shapes have attracted significant attention in the development of nano-biosensors.
Petr Otipka, Jaroslav Vlček
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Representation of the Solutions of Linear Discrete Systems with Constant Coefficients and Two Delays

open access: yesAbstract and Applied Analysis, 2014
The purpose of this paper is to develop a method for the construction of solutions to initial problems of linear discrete systems with constant coefficients and with two delays Δx(k)=Bx(k-m)+Cx(k-n)+f(k), where m,n∈ℕ, m≠n, are fixed, k=0,…,∞, B=(bij), C=(
Josef Diblík, Blanka Morávková
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

SIGNS LANGUAGE IN GRAPHICAL COMMUNICATION MECHANICAL DRAWING: THE BASIC LANGUAGE IN GRAPHICAL COMMUNICATION

open access: yesJournal of Industrial Design and Engineering Graphics, 2010
The paper presents general notions about graphical language used in engineering, the international standards used for representing objects and also the most important software applications used in Computer Aided Design for the development of products in ...
BADEA Florina, PETRESCU Ligia
doaj  

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