Results 101 to 110 of about 639,728 (301)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Descriptive norms and entrepreneurial intentions: the mediating role of anticipated inaction regret. [PDF]
Front Psychol, 2023 Bae TJ +4 more
europepmc +1 more source
International Journal of Behavioral Nutrition and Physical Activity, 2018 Background Descriptive norms (what other people do) relate to individual-level dietary behaviour and health outcome including overweight and obesity.
Suzanne J. Carroll +4 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Comparative influence of social norms on tourist behaviour in wildlife [PDF]
, 2015 Social norms can be effective factors in promoting environmental behavior. To date,the little research that does exist recommends that there is a discrepancy between what people approve (injunctive norms) of and what people actually do (descriptive ...
Jafarpour, Marjan
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Constructive Empiricism: Normative or Descriptive? [PDF]
International Journal of Philosophical Studies, 2014 In this paper, I argue that Constructive Empiricism (CE) is ambiguous between two interpretations: CE as a normative epistemology of science and CE as a descriptive philosophy of science. When they present CE, constructive empiricists write as if CE is supposed to be more than a normative epistemology of science and that it is meant to be responsible ...
openaire +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Deontic logic as a study of conditions of rationality in norm-related activities [PDF]
, 2016 The program put forward in von Wright's last works defines deontic logic as ``a study of conditions which must be satisfied in rational norm-giving activity'' and thus introduces the perspective of logical pragmatics.
Žarnić, Berislav
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Transcendental Pragmatics and Hermeneutics [PDF]
, 2004 : In which sense could transcendental pragmatics combined with a hermeneutical approach provide the social sciences with a critical oriented approach?
Hedberg, Petra
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