Results 91 to 100 of about 11,781,613 (287)

KOMUNIKASI PEMIMPIN PUSAT-DAERAH DI ERA REVOLUSI INDUSTRI 4.0

open access: yesJurnal Peurawi: Media Kajian Komunikasi Islam, 2019
Communication between central-regional leaders is a substance in building the Indonesian nation. The central leaders, both the President, the Minister, as well as the first and second echelon officials based in Jakarta, need a strategy in communicating ...
Abdul Rani Usman   +2 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Two kinds of average approximation accuracy

open access: yesCAAI Transactions on Intelligence Technology
Rough set theory places great importance on approximation accuracy, which is used to gauge how well a rough set model describes a target concept. However, traditional approximation accuracy has limitations since it varies with changes in the target ...
Qingzhao Kong   +3 more
doaj   +1 more source

Improvável – um espetáculo provavelmente bom: Relevance-theoretic analysis of interactional processes in the game Cenas improváveis

open access: yesCalidoscópio, 2011
Inspired on the British and American show Whose Line Is It Anyway?, where the public can create scenes for the actors to interpret, the Cia. Barbixas de Humor produces the performance Improvável – um espetáculo provavelmente bom (Unlikely – a likely good
Fábio José Rauen   +1 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Application of Kolcaba’s Comfort Theory in healthcare promoting adults’ comfort: a scoping review

open access: yesBMJ Open
Background Comfort is a primary goal of healthcare. Theory-informed interventions and measurement are essential for comfort enhancement.Objectives To categorise and synthesise the international literature on the application of Kolcaba’s Comfort Theory in
Yi Zhou   +4 more
doaj   +1 more source

An airspace analysis according to area navigation requirements

open access: yesAviation, 2019
Aircraft navigation within controlled airspace is carried out using on-board positioning systems capable to determine the coordinates of aircraft location with the system performance that meet navigation specifications requirements.
Ivan Ostroumov   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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