Results 71 to 80 of about 134,969 (309)
Classical descriptive set theory as a refinement of effective descriptive set theory
Abstract The (effective) Suslin–Kleene Theorem is obtained as a corollary of a standard proof of the classical Suslin Theorem, by noticing that it is mostly constructive and applying to it a naive realizability interpretation.
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
KOMUNIKASI PEMIMPIN PUSAT-DAERAH DI ERA REVOLUSI INDUSTRI 4.0
Communication between central-regional leaders is a substance in building the Indonesian nation. The central leaders, both the President, the Minister, as well as the first and second echelon officials based in Jakarta, need a strategy in communicating ...
Abdul Rani Usman +2 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Information uncertainty in management systems is a subject of research of many scientific disciplines. Research concerning a quantitative modelling of uncertainty verging on mathematics, information technology, and logic is extremely important.
Rafał Mierzwiak
doaj +1 more source
ITERATED PRIORITY ARGUMENTS IN DESCRIPTIVE SET THEORY
AbstractWe present the true stages machinery and illustrate its applications to descriptive set theory. We use this machinery to provide new proofs of the Hausdorff–Kuratowski and Wadge theorems on the structure of $\mathbf {\Delta }^0_\xi $ , Louveau and Saint Raymond’s separation theorem, and Louveau’s separation theorem.
ADAM DAY +3 more
openaire +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Inspired on the British and American show Whose Line Is It Anyway?, where the public can create scenes for the actors to interpret, the Cia. Barbixas de Humor produces the performance Improvável – um espetáculo provavelmente bom (Unlikely – a likely good
Fábio José Rauen +1 more
doaj +1 more source

