Results 141 to 150 of about 109,170 (315)

Computing Generalized Inverse Systems using Matrix Pencil Methods

open access: yes, 2001
We address the numerically reliable computation of generalized inverses of rational matrices in descriptor state-space representation. We put particular emphasis on two classes of inverses: the weak generalized inverse and the Moore-Penrose pseudoinverse.
Varga, A., Varga, Andras
core  

Sequential Complexity as a Descriptor for Musical Similarity

open access: yes, 2014
We propose string compressibility as a descriptor of temporal struc-ture in audio, for the purpose of determining musical similarity. Our descriptors are based on computing track-wise compression rates of quan-tised audio features, using multiple ...
Mauch, M   +5 more
core   +1 more source

descriptor

open access: yes
Citation: 'descriptor' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11436 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Computation of least order solutions of linear rational equations

open access: yes, 2004
We propose a numerically reliable approach for computing solutions of least McMillan order of linear equations with rational matrix coefficients. The main computational ingredients are the orthogonal reduction of the associated system matrix pencil to a ...
A. Varga, Varga, Andras
core  

On computing inner-outer factorizations of periodic systems

open access: yes, 2013
A numerically reliable state space algorithm is proposed for computing inner-outer factorizations of causal periodic descriptor systems. The main computational ingredients are the computation of a special condensed Kronecker-like form of periodic ...
Varga, Andreas, Andreas Varga
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Spherical harmonics coeffcients for ligand-based virtual screening of cyclooxygenase inhibitors

open access: yes, 2011
Background: Molecular descriptors are essential for many applications in computational chemistry, such as ligand-based similarity searching. Spherical harmonics have previously been suggested as comprehensive descriptors of molecular structure and ...
Angioni, Carlo   +25 more
core   +1 more source

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