Results 161 to 170 of about 131,957 (312)

Efficient clustering and quantisation of SIFT features: Exploiting characteristics of the SIFT descriptor and interest region detectors under image inversion

, 2011
The SIFT keypoint descriptor is a powerful approach to encoding local image description using edge orientation histograms. Through codebook construction via k-means clustering and quantisation of SIFT features we can achieve image retrieval treating ...
Lewis, Paul, Samangooei, Sina, Hare, Jonathon   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

PREDICT OF THE SMALL SIZE OBJECT POSITION ON THE VIDEO STREAM FRAMES FROM THE BOARD OF UNMANNED AERIAL VEHICLE

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
Algorithms of video stabilization from unmanned aerial vehicle board and search of small size targets on the video sequence frames with the prediction are proposed.
I. A. Baryskievic
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Statistical layout of improved image descriptor for pedestrian detection

, 2010
An automatic and robust approach for pedestrian detection is proposed in natural scene images, even in the presence of clutter and occlusion. An improved statistical descriptor is designed to encode more support vectors, and the dimensionality reduction ...
Zhuang Y(庄严), Wang W(王伟), Bai M(白明)   +2 more
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

What the Controlled-Vocabulary Layer Cannot Say About Where a Depression Biomarker Was Measured: A Meta Research Analysis of MeSH Sampling-Compartment Coding, January 2024-June 2026. [PDF]

Actas Esp Psiquiatr
Paganin W.
europepmc   +1 more source