Results 181 to 190 of about 131,957 (312)

Machine Learning and Structural Analysis for Generation-Wise Selection of Perylene Diimide Dendrimers Based on Topological Compatibility With Drug Molecules. [PDF]

ChemistryOpen
Bibi Z, Ali J, Irshad S, Ghafar MS, Ali Y, Shang Y.   +5 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

MambaAdapt: Joint Descriptor-Alignment Learning with Mamba-Transformer Fusion for Robust Long-Term VPR. [PDF]

Sensors (Basel)
Fahad M, He D, Yu W, Truong TK.
europepmc   +1 more source

Complementing a region descriptor for shape retrieval

, 2008
In this paper, we propose to complement a region descriptor for shape retrieval with a contour descriptor; the descriptor thus obtained is a composite descriptor.
Atul Sajjanhar (13059588), D Zhang (660807), W Zhou (7715300), G Lu (7647290)   +3 more
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

DA-MoE: descriptor-attention mixture-of-experts for multi-class gastrointestinal disease classification. [PDF]

Front Oncol
Xu Y, Liu L, Tang M.
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Enhanced Generalization through Atomic Embeddings and Cross-Element Parameterization. [PDF]

J Chem Inf Model
Taleblou M, Pellegrini F, de Gironcoli S.   +2 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

QSAR Modeling and Fragment Contribution Analysis of N-Benzyltryptamines at Human 5-HT2 Receptor Subtypes. [PDF]

Molecules
Đorđević V, Binić I, Petrović J, Stojanov J, Mitić Ž, Veselinović AM.   +5 more
europepmc   +1 more source