Results 101 to 110 of about 2,107,565 (334)

Prothrombotic Activation of Platelet Pannexin‐1 Channels in Antiphospholipid Syndrome

Arthritis &Rheumatology, EarlyView.
Objective ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. The objective of this study was to evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired ...
Bruna de Moraes Mazetto Fonseca, Somanathapura K. NaveenKumar, Srilakshmi Yalavarthi, Kavya Sugur, Thalia G. Newman, Claire K. Hoy, Cyrus Sarosh, Jordan K. Schaefer, Ajay Tambralli, Jacqueline A. Madison, Yu Zuo, Fernanda A. Orsi, Michael Holinstat, Jason S. Knight   +13 more
wiley   +1 more source

Taking care of our future doctors: a service evaluation of a medical student mental health service

BMC Medical Education, 2020
Background Studies suggest medical students experience high levels of mental distress during training but are less likely, than other students, to access care due to stigma and concerns regarding career progression.
Rebecca Jacob, Tsz-yan Li, Zoe Martin, Amanda Burren, Peter Watson, Rhian Kant, Richard Davies, Diana F. Wood   +7 more
doaj   +1 more source

The role of the neuromodulator adenosine in alcohols actions. [PDF]

, 1997
The interaction between the neuromodulator adenosine and adenosine receptors on the surface of neurons modifies the neurons responses to neurotransmitters.
Diamond, Ivan, Dohrman, D, Gordon, A
core  

Medical students' initial experiences of the dissection room and interaction with body donors: A qualitative study of professional identity formation, educational benefits, and the experience of Pasifika students

Anatomical Sciences Education, EarlyView.
Abstract The first experience of medical students in the dissecting room (DR) likely influences professional identity formation (PIF). Sparse data exist exploring how exposure to the DR and body donors without undertaking dissection influences PIF, or how culture may influence this experience.
Jacob Madgwick, Lynley Anderson, Jon Cornwall   +2 more
wiley   +1 more source

Using artificial intelligence thanabots as “thanatobots” to assist anatomy learning and professional development: Ghosts masquerading as opportunity?

Anatomical Sciences Education, EarlyView.
Thanabots—AI‐generated digital representations of deceased donors—could enhance anatomy education by linking medical history with anatomy and fostering humanistic engagement. However, their use poses ethical questions and carries psychological risks, including issues around consent, authenticity, and emotional harm.
Jon Cornwall, Sabine Hildebrandt
wiley   +1 more source

Eye movement desensitisation and reprocessing for offence-related trauma in a mentally disordered sexual offender [PDF]

, 2013
Research demonstrates a high incidence of offence-related trauma in mentally disordered offenders convicted of violent and sexual offences. The adaptive information processing (AIP) model offers a theoretical framework for understanding the hypothesised ...
Clark, Lauren, Gannon, Theresa A., Kingham, Michael, Tyler, Nichola   +3 more
core   +1 more source

Penicillin allergy de‐labelling in the critical care unit: Simulations to design an intravenous drug provocation test that mirrors the plasma profile of an enteral challenge

British Journal of Clinical Pharmacology, EarlyView.
The majority of penicillin allergy labels are incorrect and a label of penicillin allergy is associated with worse outcomes and increased use of healthcare services. Penicillin allergy assessment and de‐labelling may be considered in critically ill patients. An oral penicillin challenge is a common component of most penicillin allergy protocols.
Cleodie Swire, Sean Keane, Reya Vinay Shah, Toqa El‐Nahhas, Iao Lei, Salma Alamin, Niall Conlon, Dagan Osborne Lonsdale   +7 more
wiley   +1 more source

Paradigm clashes and progress: a personal reflection on a 50-year association with ABCT [PDF]

, 2016
Why is ABCT a successful, vibrant, and growing association when most other professional associations are withering on the vine? Since the first annual meeting of the organization, which I was privileged to attend, I have witnessed repeated changes in ...
Barlow, David H.
core   +1 more source

Successful kidney transplantation across a positive complement-dependent cytotoxicity crossmatch by using C1q assay-directed, bortezomib-assisted desensitization

Medicine, 2017
Rationale: Human leukocyte antigen (HLA) is the major immunologic barrier in kidney transplantation (KT). Various desensitization protocols to overcome the HLA barrier have increased the opportunity for transplantation in sensitized patients. In addition,
Juhan Lee, Borae G. Park, H. Jeong, Youn Hee Park, S. Kim, B. Kim, Hye Jin Kim, K. Huh, H. Jeong, Yu Seun Kim   +9 more
semanticscholar   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source