Results 81 to 90 of about 2,288,448 (331)

Successful Deferasirox Rechallenge and Treating Through Reaction in a Patient with Challenge-Proven Mild Immediate Reaction: A Case Report

Journal of Asthma and Allergy, 2020
Mongkhon Sompornrattanaphan,1 Thanachit Krikeerati,1,2 Chamard Wongsa,1 Torpong Thongngarm,1 Kittika Yampayon3 1Division of Allergy and Clinical Immunology, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok ...
Sompornrattanaphan M, Krikeerati T, Wongsa C, Thongngarm T, Yampayon K   +4 more
doaj  

A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site [PDF]

, 2004
To study conformational transitions at the muscle nicotinic acetylcholine (ACh) receptor (nAChR), a rhodamine fluorophore was tethered to a Cys side chain introduced at the beta-19' position in the M2 region of the nAChR expressed in Xenopus oocytes ...
Auyeung, Vincent C., Bezanilla, Francisco, Chanda, Baron, Dahan, David S., Dibas, Mohammed I., Dougherty, Dennis A., Lester, Henry A., Petersson, E. James   +7 more
core  

Olaparib Desensitization in a Patient with Recurrent Peritoneal Cancer.

New England Journal of Medicine, 2018
Desensitization for Olaparib Hypersensitivity Some patients have immediate hypersensitivity responses to olaparib therapy.
J. Grabowski, J. Sehouli, Joanna Glajzer, M. Worm, T. Zuberbier, M. Maurer, J. Fluhr   +6 more
semanticscholar   +1 more source

Auditory Hyperresponsivity in Chronic Back Pain: A Randomized Controlled Trial of Pain Reprocessing Therapy

Annals of Neurology, EarlyView.
Objective Heightened sensitivity to noxious stimulation is a hallmark of chronic pain. Emerging evidence suggests heightened unpleasantness to non‐noxious (eg, auditory) aversive stimulation also characterizes chronic pain, but its magnitude, neural mechanisms, and treatment modifiability remain unknown.
Alina E. C. Panzel, Christian Büchel, Andrew Leroux, Tor D. Wager, Yoni K. Ashar   +4 more
wiley   +1 more source

The increasing role of the allergist in the management of infusion reactions at the Oncology Infusion Center

Frontiers in Allergy
BackgroundHypersensitivity reactions to chemotherapy disrupt treatment schedules and compromise patient outcomes. Rapid Drug Desensitization (RDD) enables patients to tolerate future treatments after an allergy workup.
Julián Borrás Cuartero, Maria Cruz Torres Górriz, Maria Cruz Torres Górriz, Maria Cruz Torres Górriz, Cristina Isabel Stein Coronado, Cristina Isabel Stein Coronado, Adrián Germán Sánchez, Adrián Germán Sánchez, Cristina Giovanna Pesántez Méndez, Cristina Giovanna Pesántez Méndez, Maria Dolores Latorre Ibáñez, Ernesto Enrique, Ernesto Enrique, Ernesto Enrique   +13 more
doaj   +1 more source

Paradigm clashes and progress: a personal reflection on a 50-year association with ABCT [PDF]

, 2016
Why is ABCT a successful, vibrant, and growing association when most other professional associations are withering on the vine? Since the first annual meeting of the organization, which I was privileged to attend, I have witnessed repeated changes in ...
Barlow, David H.
core   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

Angewandte Chemie International Edition, EarlyView.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Metabotropic glutamate receptor 2/3 (mGluR2/3) activation suppresses TRPV1 sensitization in mouse, but not human sensory neurons [PDF]

, 2018
The use of human tissue to validate putative analgesic targets identified in rodents is a promising strategy for improving the historically poor translational record of preclinical pain research.
Baranger, David A.A., Gereau, Robert W, McIlvried, Lisa V, Pullen, Melanie Y, Sheahan, Tayler D, Valtcheva, Manouela V   +5 more
core   +2 more sources

B cell repertoires in HLA-sensitized kidney transplant candidates undergoing desensitization therapy

Journal of Translational Medicine, 2017
Kidney transplantation is the most effective treatment for end-stage renal disease. Sensitization refers to pre-existing antibodies against human leukocyte antigen (HLA) protein and remains a major barrier to successful transplantation.
J. Beausang, H. C. Fan, R. Sit, M. Hutchins, K. Jirage, R. Curtis, Edward Hutchins, S. Quake, S. Quake, J. Yabu   +9 more
semanticscholar   +1 more source

Analysis of anxiety levels and perceived satisfaction after a first encounter with human body prosection among nursing undergraduates based on their self‐perceived presession nervousness: An observational study

Anatomical Sciences Education, EarlyView.
Abstract Human body prosection practices are a crucial educational tool for learning anatomy. However, the first exposure to donors' material can cause anxiety, which may affect students' learning experiences and emotional adjustment. This observational study aimed to analyze anxiety levels (state and trait) before and after a prosection session in ...
Mónica Grande‐Alonso, María Teresa García‐de Juan, Irene Méndez‐Mesón, Soledad Aguado‐Henche, Rafael Ramírez‐Carracedo, Roberto Fernández‐Baillo, Mauricio Hernández‐Fernández, Alba Sebastián‐Martín, Rafael Moreno‐Gómez‐Toledano   +8 more
wiley   +1 more source