Results 71 to 80 of about 2,288,448 (331)

Better understanding of childhood asthma, towards primary prevention – are we there yet? Consideration of pertinent literature [version 1; referees: 2 approved]

F1000Research, 2017
Asthma is a chronic disease, characterized by reversible airway obstruction, airway inflammation and hyper-reactivity. The prevalence of asthma has risen dramatically over the past decade, affecting around 300,000,000 people.
Michal Gur, Fahed Hakim, Lea Bentur
doaj   +1 more source

Lidocaine spray 10% prior to intravenous catheterisation in dogs

Acta Veterinaria Scandinavica, 2022
A common and to some degree painful procedure in veterinary practice is to insert an intra-venous catheter. In both human and veterinary medicine, a topical mixture of lidocaine and prilocaine (EMLA cream) has shown to reduce the pain, however a period ...
Emma Hoeberg, Tonje Loken Kolstad, Liisa Martine Moller, Silje Kristine Rosvold, Maren Heggernes Softeland, Henning Andreas Haga, Andreas Lervik   +6 more
doaj   +1 more source

It is never as good the second time around: Brain areas involved in salience processing habituate during repeated drug cue exposure in treatment engaged abstinent methamphetamine and opioid users

NeuroImage, 2021
The brain response to drug-related cues is an important marker in addiction-medicine. However, the temporal dynamics of this response in repeated exposure to cues are not well known.
Hamed Ekhtiari, Rayus Kuplicki, Robin L. Aupperle, Martin P. Paulus   +3 more
doaj   +1 more source

Trauma-Focused Interventions: A Clinical Practice Analysis [PDF]

, 2018
This paper presents a systematic review of trauma-treatment interventions, which have different theoretical perspectives on trauma etiology and its application. The empirical findings of these trauma treatment therapies are presented.
Carbajal, Jose
core   +1 more source

Eye movement desensitisation and reprocessing for offence-related trauma in a mentally disordered sexual offender [PDF]

, 2013
Research demonstrates a high incidence of offence-related trauma in mentally disordered offenders convicted of violent and sexual offences. The adaptive information processing (AIP) model offers a theoretical framework for understanding the hypothesised ...
Clark, Lauren, Gannon, Theresa A., Kingham, Michael, Tyler, Nichola   +3 more
core   +1 more source

Desensitization Using Bortezomib and High-dose Immunoglobulin Increases Rate of Deceased Donor Kidney Transplantation

Medicine, 2016
Combination therapy of intravenous immunoglobulin (IVIG) and rituximab showed a good transplant rate in highly sensitized wait-listed patients for deceased donor kidney transplantation (DDKT), but carried the risk of antibody-mediated rejection.
J. Jeong, Enkthuya Jambaldorj, H. Kwon, Myung-Gyu Kim, Hyeji Im, H. Jeon, J. In, Miyeun Han, T. Koo, Junho Chung, E. Song, C. Ahn, Jaeseok Yang   +12 more
semanticscholar   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Low Molecular Weight mRNA Encodes a Protein That Controls Serotonin 5-HT_(1c) and Acetylcholine M_1 Receptor Sensitivity in Xenopus Oocytes [PDF]

, 1991
Serotonin 5-HT_(1c) and acetylcholine M_1 receptors activate phosphoinositidase, resulting in an increased formation of IP_3 and 1,2 diacylglycerol.
Davidson, N., Hoger, J. H., Labarca, C., Lester, H. A., Walter, A. E., Yu, L.   +5 more
core  

Successful Desensitization with Crizotinib after Crizotinib-induced Liver Injury in ROS1-rearranged Lung Adenocarcinoma

Internal medicine, 2019
Crizotinib has been approved for patients with advanced lung adenocarcinoma harboring rearrangements of the c-ROS-1 (ROS1) and anaplastic lymphoma kinase (ALK) genes. We report a patient with ROS1-rearranged lung adenocarcinoma who developed a crizotinib-
T. Ota, N. Masuda, K. Matsui, Takao Yamada, N. Tanaka, Shunsuke Fujimoto, M. Fukuoka   +6 more
semanticscholar   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source