Results 51 to 60 of about 2,288,448 (331)

Successful Desensitization with Imlifidase and Daratumumab in a Highly Immunized, Crossmatch Positive, Blood Group-Incompatible Living-Donor Re-Transplant Recipient with Systemic Lupus Erythematosus and Antiphospholipid Syndrome

Transfusion Medicine and Hemotherapy
Introduction: The transplantation of highly sensitized patients remains a major obstacle. Immunized patients wait longer for a transplant if not prioritized, and if transplanted, their transplant outcome is worse.
E. Schrezenmeier, Mira Choi, B. Globke, T. Dörner, Alexandra Leimbach, B. Osmanodja, A. Schramm, Kerstin Amann, K. Eckardt, K. Budde, R. Öllinger, N. Lachmann, F. Halleck   +12 more
semanticscholar   +1 more source

Usefulness of Rapid Desensitization Therapy for Severe Rash Caused by Molecularly Targeted Drugs Used in the Treatment of Non-small-cell Lung Cancer

Internal medicine, 2020
Molecular-targeted drugs (MTDs), such as epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and anaplastic lymphoma kinase inhibitors, are used to treat non-small-cell lung cancer (NSCLC).
Maki Nagase, Nobuharu Ohshima, M. Kawashima, M. Ohgiya, Miki Ikeda, Y. Morio, A. Tamura   +6 more
semanticscholar   +1 more source

The feasibility of organ transplantation during the COVID-19 outbreak: experiences from South Korea

Korean Journal of Transplantation, 2020
Background : The coronavirus disease 2019 (COVID-19) has forced healthcare systems to reduce transplant activities in order to preserve resources and minimize the risk of nosocomial transmission.
Juhan Lee, Eun Jin Kim, Kyong Ihn, Jae Geun Lee, Dong Jin Joo, Myoung Soo Kim, Soon Il Kim, Yu Seun Kim, Kyu Ha Huh   +8 more
doaj   +1 more source

Ethanol reversal of tolerance to the respiratory depressant effects of morphine [PDF]

, 2015
Opioids are the most common drugs associated with unintentional drug overdose. Death results from respiratory depression. Prolonged use of opioids results in the development of tolerance but the degree of tolerance is thought to vary between different ...
A Fugelstad, A Fugelstad, Abi Lyndon, AJ Ruttenber, Anne Lingford-Hughes, AR Lingford-Hughes, B Levine, BM Mathers, CA Paronis, Chris Bailey, CK Kuo, CN Lessov, CP Bailey, CP Bailey, CP Bailey, E Kelly, E Valjent, Eamonn Kelly, EB Rex, EJ Waite, F Chen, FL Smith, FL Smith, Graeme Henderson, GS Ling, H Sakakibara, HW Matthes, HY Lin, I Rodriguez-Martin, J Llorente, J McPherson, J Reneau, JM White, Joanne Roberts, John MacLachlan, JT Williams, JW Lewis, KL McGilliard, L He, LC Hull, LC Saland, LJ Sim-Selley, LM Bohn, LQ Hong-Brown, M Aliczki, M Hickman, M Hickman, M Inoue, M Pierce, Matthew Hickman, N Quillinan, NG Shah, R Cornish, R Romberg, Rob Hill, S Darke, S Darke, S Kishioka, Sarah Withey, SJ Slater, SV Dighe, TC Green, Yvonne Kershaw   +62 more
core   +5 more sources

Lymphoid differentiation of hematopoietic stem cells requires efficient Cxcr4 desensitization

Journal of Experimental Medicine, 2017
The CXCL12/CXCR4 signaling exerts a dominant role in promoting hematopoietic stem and progenitor cell (HSPC) retention and quiescence in bone marrow.
C. Freitas, M. Wittner, Julie V. Nguyen, V. Rondeau, Vincent Biajoux, Marie-Laure Aknin, F. Gaudin, S. Beaussant-Cohen, Y. Bertrand, C. Bellanné-Chantelot, J. Donadieu, F. Bachelerie, M. Espéli, A. Dalloul, F. Louache, K. Balabanian   +15 more
semanticscholar   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Stimulation of electro-olfactogram responses in the main olfactory epithelia by airflow depends on the type 3 adenylyl cyclase [PDF]

, 2012
Cilia of olfactory sensory neurons are the primary sensory organelles for olfaction. The detection of odorants by the main olfactory epithelium (MOE) depends on coupling of odorant receptors to the type 3 adenylyl cyclase (AC3) in olfactory cilia.
Chen, Xuanmao, Storm, Daniel R., Xia, Zhengui   +2 more
core   +2 more sources

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

War psychic impairment in military personnel: mechanism and its prevention in a psychological perspective

Di-san junyi daxue xuebao, 2020
War psychic impairment refers to the psychological reactions or mental dysfunction (psychological depletion) in military personnel caused by physical and psychological stresses from the battlefield environment, which has physiological, psychological ...
FENG Zhengzhi, XU Huimin
doaj   +1 more source