Results 31 to 40 of about 2,288,448 (331)

Hypersensitivity Reactions to Monoclonal Antibodies in Children

Medicina, 2020
Biologic drugs are widely used in pediatric medicine. Monoclonal antibodies (mAbs) in particular are a therapeutic option for rheumatic, autoinflammatory and oncologic diseases.
Francesca Mori, Francesca Saretta, Annamaria Bianchi, Giuseppe Crisafulli, Silvia Caimmi, Lucia Liotti, Paolo Bottau, Fabrizio Franceschini, Claudia Paglialunga, Giampaolo Ricci, Angelica Santoro, Carlo Caffarelli   +11 more
doaj   +1 more source

Interdisciplinary Healthcare Team Experience of Carboplatin and Oxaliplatin Desensitizations in a Tertiary Referral University Hospital

Journal of Asthma and Allergy, 2023
Ceyda Tunakan Dalgic,1 Asuman Camyar,1 Nihal Mete Gokmen,1 Sukriye Miray Kilincer Bozgul,2 Mehmet Zuhuri Arun,3 Zehra Tuba Karaman,2 Elif Ertuna3 1Department of Internal Medicine, Division of Allergy and Immunology, Faculty of Medicine, Ege University ...
Tunakan Dalgic C, Camyar A, Mete Gokmen N, Kilincer Bozgul SM, Arun MZ, Karaman ZT, Ertuna E   +6 more
doaj  

A case report of successful renal transplantation in an ABO incompatible patient with a preformed donor-specific antibody and negative CDC human leukocyte antigens crossmatch

Saudi Journal of Kidney Diseases and Transplantation, 2018
ABO incompatibility and preformed antibodies against the human leukocyte antigen (HLA) are two impermissible barriers to a successful renal transplantation, especially in highly sensitized patient population.
Mohit Chowdhry, Raj Nath Makroo, Brinda Kakkar, Sanjiv Jasuja, Gaurav Sagar, Yogita Thakur   +5 more
doaj   +1 more source

Drug Hypersensitivity and Anaphylaxis in Cancer and Chronic Inflammatory Diseases: The Role of Desensitizations

Frontiers in Immunology, 2017
Drug allergy is a rising problem in the twenty-first century which affects all populations and races, children, and adults, and for which the recognition, diagnosis, management, and treatment is still not well standardized. Classical and new chemotherapy
Mariana Castells
doaj   +1 more source

Positive allosteric modulators of the a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor [PDF]

, 2010
L-glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS) and plays a fundamental role in the control of motor function, cognition and mood.
Grove, Simon J .A., Jamieson, Craig, Maclean, John K. F., Morrow, John A., Rankovic, Zoran   +4 more
core   +1 more source

Current Insights into Immunotherapy Approaches for Food Allergy

ImmunoTargets and Therapy, 2021
Jessica D Macdougall,1 A Wesley Burks,1 Edwin H Kim2 1Department of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC, USA; 2Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC ...
Macdougall JD, Burks AW, Kim EH
doaj  

CRISPR/Cas9-mediated generation and analysis of N terminus polymorphic models of β2AR in isogenic hPSC-derived cardiomyocytes

Molecular Therapy: Methods & Clinical Development, 2021
During normal- and patho-physiological situations, the behavior of the beta2-adrenoreceptor (β2AR) is influenced by polymorphic variants. The functional impact of such polymorphisms has been suggested from data derived from genetic association studies ...
Alexander Kondrashov, Nurul A.N. Mohd Yusof, Alveera Hasan, Joëlle Goulding, Thusharika Kodagoda, Duc M. Hoang, Nguyen T.N. Vo, Tony Melarangi, Nazanin Dolatshad, Julia Gorelik, Stephen J. Hill, Sian E. Harding, Chris Denning   +12 more
doaj   +1 more source

No diffuse intrahepatic biliary stricture after ABO-incompatible adult living donor liver transplantation using tailored rituximab-based desensitization protocol

Annals of Translational Medicine, 2020
Background Rituximab (RTx) desensitization protocol offered good outcome in ABO-incompatible (ABOi) living donor liver transplantation (LDLT). However, diffuse intrahepatic biliary stricture (DIHBS) is still inevitable hurdle.
K. Natsuda, T. Murokawa, Kwang-Wonng Lee, K. Yoon, S. Hong, Jeong‐Moo Lee, Jae-Hyung Cho, N. Yi, K. Suh   +8 more
semanticscholar   +1 more source

Dopamine-D1 and δ-opioid receptors co-exist in rat striatal neurons [PDF]

, 2006
Cocaine’s enhancement of dopaminergic neurotransmission in the mesolimbic pathway plays a critical role in the initial reinforcing properties of this drug. However, other neurotransmitter systems are also integral to the addiction process.
Ambrose-Lanci, L. M., Gallagher, S. M., Unterwald, E. M., Van Bockstaele, E. J.   +3 more
core   +2 more sources

Efficacy and tolerability of desensitization in the treatment of delayed drug hypersensitivities to anti-tuberculosis medications.

Respiratory Medicine, 2019
BACKGROUND Delayed drug hypersensitivity to first-line anti-tuberculosis medication is a major challenge in tuberculosis treatment. OBJECTIVE This study was performed to investigate the efficacy/tolerability of desensitization therapy in treatment of ...
G. Ban, Yoonsoo Jeong, So-Hee Lee, Seung-Soo Shin, Y. Shin, Hae‐Sim Park, Seung-Hyun Kim, Y. Ye   +7 more
semanticscholar   +1 more source