Results 11 to 20 of about 2,288,448 (331)

Tocilizumab Evaluation in HLA-Desensitization before Kidney Transplantation as an Add-On Therapy to Apheresis: The TETRA Study

Journal of Clinical Medicine, 2023
Background: Desensitization strategies improve access to transplantation in highly sensitized kidney transplant candidates. Tocilizumab could be a valuable addition to more traditional desensitization regimens.
T. Jouvé, Mélanie Daligault, Johan Noble, Florian Terrec, F. Imerzoukene, C. Dard, B. Bardy, P. Malvezzi, L. Rostaing   +8 more
semanticscholar   +1 more source

Cough desensitization treatment for patients with refractory chronic cough: results of a second pilot randomized control trial

BMC Pulmonary Medicine, 2023
Objective The purpose of this study was to collect pilot efficacy data on a novel treatment for refractory chronic cough (RCC), which we call cough desensitization treatment (CDT).
Laurie J. Slovarp, Jane E. Reynolds, Sophia Tolbert, Sarah Campbell, S. Welby, Paige Morkrid   +5 more
semanticscholar   +1 more source

Desensitization in patients with hypersensitivity to platinum and taxane in gynecological cancers

Cancer Medicine, 2023
Exposure to paclitaxel and carboplatin has the risk of developing hypersensitivity reactions (HSRs), which could necessitate using less effective treatments to avoid anaphylaxis.
T. Zwimpfer, K. Scherer, A. Schötzau, V. Heinzelmann-Schwarz, K. Hartmann, Marcus Vetter, Céline Montavon   +6 more
semanticscholar   +1 more source

β-Adrenergic Receptor Desensitization/Down-Regulation in Heart Failure: A Friend or Foe?

Frontiers in Cardiovascular Medicine, 2022
Cardiac sympathetic activation, mediated by β-adrenergic receptors (β-ARs), normally increases cardiac contraction and relaxation. Accomplishing this task requires a physiological, concerted Ca2+ signaling, being able to increase Ca2+ release from ...
Abrahim Mahmood, Kinza Ahmed, Youhua Zhang   +2 more
semanticscholar   +1 more source

Desensitization for the prevention of drug hypersensitivity reactions

The Korean Journal of Internal Medicine, 2022
Drug desensitization is the temporary induction of tolerance to a sensitized drug by administering slow increments of the drug, starting from a very small amount to a full therapeutic dose.
Sung-Yoon Kang, J. Seo, H. Kang
semanticscholar   +1 more source

Cough desensitization treatment: A randomized, sham-controlled pilot trial for patients with refractory chronic cough.

Respiratory Medicine, 2022
BACKGROUND The purpose of this study was to determine feasibility of treating refractory chronic cough (RCC) with progressive doses of capsaicin paired with cough suppression.
Laurie J. Slovarp, Jane E. Reynolds, Bozarth Dailey, Popp Sarah, Campbell Sarah, M. Paige   +5 more
semanticscholar   +1 more source

Tocilizumab and Desensitization in Kidney Transplant Candidates: Personal Experience and Literature Review

Journal of Clinical Medicine, 2021
Desensitization (DES) allows kidney transplantation for highly HLA-sensitized subjects. Due to the central role of IL-6 in the immunological response, tocilizumab may improve DES efficacy.
Jules Weinhard, Johan Noble, T. Jouvé, P. Malvezzi, L. Rostaing   +4 more
semanticscholar   +1 more source

Management of chronic rhinosinusitis with nasal polyps in Samter triad by low-dose ASA desensitization or dupilumab

Medicine, 2021
Samter triad is a chronic condition where patients suffer from intolerance to aspirin, recurring nasal polyposis and bronchial asthma. Causative treatment is often hard.
M. Bertlich, F. Ihler, I. Bertlich, B. Weiss, M. Gröger, F. Haubner   +5 more
semanticscholar   +1 more source

Improving CPAP Adherence for Obstructive Sleep Apnea: A Practical Application Primer on CPAP Desensitization

MedEdPORTAL, 2020
Introduction Obstructive sleep apnea (OSA) is a common medical condition with well-established morbidity and mortality. Continuous positive airway pressure (CPAP) is a highly effective treatment prescribed to most individuals with OSA that has documented
Yelena Chernyak
doaj   +1 more source

B Cell-Derived Extracellular Vesicles Reveal Residual B Cell Activity in Kidney Graft Recipients Undergoing Pre-Transplant Desensitization

Frontiers in Medicine, 2021
Background: Living-donor kidney transplant (LDKT) recipients undergoing desensitization for Human Leukocyte Antigen (HLA)-incompatibility have a high risk of developing antibody-mediated rejection (ABMR).
D. Cucchiari, Valeria Tubita, J. Rovira, M. Ramirez-Bajo, E. Bañon-maneus, M. Lazo-Rodríguez, Natalia Hierro-García, F. Borràs, P. Ventura-Aguiar, Gaston J. Piñeiro, J. Martorell., L. Peri, M. Musquera, A. Hertig, F. Oppenheimer, J. Campistol, F. Diekmann, I. Revuelta   +17 more
semanticscholar   +1 more source